RECRUITING

Incremental Vestibulo-ocular Reflex Adaptation As a Novel Treatment for Dizziness in People with Multiple Sclerosis

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Conditions

Multiple SclerosisTreatment of multiple sclerosisIncremental Vestibulo-ocular Reflex AdaptationDizziness in people with multiple sclerosis

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The study aims to study the effects of a novel treatment for vestibular symptoms in people with multiple sclerosis. The main objective is to determine whether daily personalized gaze stabilization training is more beneficial than intermittent gaze stability training in people with multiple sclerosis.

Official Title

Daily Versus Intermittent Incremental Vestibulo-ocular Reflex Adaptation As a Novel Treatment for Dizziness in People with Multiple Sclerosis

Quick Facts

Study Start:2025-04
Study Completion:2027-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06495138

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 89 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Neurologist-confirmed diagnosis of primary progressive or relapsing and remitting MS per the 2017 Revision of the McDonald Criteria and the Magnetic Resonance Imaging in MS
  2. * Fluent in speaking and understanding English
  3. * Have self-reported vestibular symptoms of dizziness, imbalance, and/or a history of at least two falls in the prior 12 months
  1. * Clinically isolated syndrome or radiologically isolated syndrome.
  2. * Worsening MS symptoms during the prior 60 days
  3. * Immunotherapy change in the prior 60 days
  4. * Self-reported cognitive impairment that limits independence with basic and instrumental activities of daily living
  5. * Systolic blood pressure \> 180 mmHg and/or diastolic blood pressure \> 90 mmHg at rest
  6. * Static visual acuity with correction of worse than 1.0 logMAR
  7. * Manifest ocular misalignment ≥ 5 diopters (e.g., tropia, lazy eye, strabismus}
  8. * Convergence insufficiency
  9. * Intra-nuclear ophthalmoplegia
  10. * Benign paroxysmal positional vertigo
  11. * Major orthopedic conditions that limit cervical spine range of motion or that alter walking
  12. * Self-reported current or potential for pregnancy during enrollment
  13. * Ongoing participation in vestibular rehabilitation for dizziness

Contacts and Locations

Study Contact

Colin Grove, PT, DPT, MS, PhD
CONTACT
(404) 712-8685
colin.r.grove@emory.edu
Colin Grove
CONTACT
(404) 712-8685
colin.r.grove@emory.edu

Principal Investigator

Colin Grove, PT, MS, DPT, PhD
PRINCIPAL_INVESTIGATOR
Emory University

Study Locations (Sites)

Emory Univeristy
Atlanta, Georgia, 30329
United States

Collaborators and Investigators

Sponsor: Emory University

  • Colin Grove, PT, MS, DPT, PhD, PRINCIPAL_INVESTIGATOR, Emory University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04
Study Completion Date2027-03

Study Record Updates

Study Start Date2025-04
Study Completion Date2027-03

Terms related to this study

Keywords Provided by Researchers

  • Treatment of multiple sclerosis
  • Incremental Vestibulo-ocular Reflex Adaptation
  • Dizziness in people with multiple sclerosis

Additional Relevant MeSH Terms

  • Multiple Sclerosis