Incremental Vestibulo-ocular Reflex Adaptation As a Novel Treatment for Dizziness in People with Multiple Sclerosis

Description

The study aims to study the effects of a novel treatment for vestibular symptoms in people with multiple sclerosis. The main objective is to determine whether daily personalized gaze stabilization training is more beneficial than intermittent gaze stability training in people with multiple sclerosis.

Conditions

Multiple Sclerosis

Study Overview

Study Details

Study overview

The study aims to study the effects of a novel treatment for vestibular symptoms in people with multiple sclerosis. The main objective is to determine whether daily personalized gaze stabilization training is more beneficial than intermittent gaze stability training in people with multiple sclerosis.

Daily Versus Intermittent Incremental Vestibulo-ocular Reflex Adaptation As a Novel Treatment for Dizziness in People with Multiple Sclerosis

Incremental Vestibulo-ocular Reflex Adaptation As a Novel Treatment for Dizziness in People with Multiple Sclerosis

Condition
Multiple Sclerosis
Intervention / Treatment

-

Contacts and Locations

Atlanta

Emory Univeristy, Atlanta, Georgia, United States, 30329

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Neurologist-confirmed diagnosis of primary progressive or relapsing and remitting MS per the 2017 Revision of the McDonald Criteria and the Magnetic Resonance Imaging in MS
  • * Fluent in speaking and understanding English
  • * Have self-reported vestibular symptoms of dizziness, imbalance, and/or a history of at least two falls in the prior 12 months
  • * Clinically isolated syndrome or radiologically isolated syndrome.
  • * Worsening MS symptoms during the prior 60 days
  • * Immunotherapy change in the prior 60 days
  • * Self-reported cognitive impairment that limits independence with basic and instrumental activities of daily living
  • * Systolic blood pressure \> 180 mmHg and/or diastolic blood pressure \> 90 mmHg at rest
  • * Static visual acuity with correction of worse than 1.0 logMAR
  • * Manifest ocular misalignment ≥ 5 diopters (e.g., tropia, lazy eye, strabismus}
  • * Convergence insufficiency
  • * Intra-nuclear ophthalmoplegia
  • * Benign paroxysmal positional vertigo
  • * Major orthopedic conditions that limit cervical spine range of motion or that alter walking
  • * Self-reported current or potential for pregnancy during enrollment
  • * Ongoing participation in vestibular rehabilitation for dizziness

Ages Eligible for Study

18 Years to 89 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Emory University,

Colin Grove, PT, MS, DPT, PhD, PRINCIPAL_INVESTIGATOR, Emory University

Study Record Dates

2027-03