RECRUITING

Mifepristone vs Misoprostol

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The Investigator team hypothesizes that in a randomized trial comparing mifepristone-alone or misoprostol-alone for cervical preparation for procedural abortions at 12 to 16 weeks in hospital-based care, the proportion of patients who achieve successful cervical dilation will be different between the study groups.

Official Title

Mifepristone Versus Misoprostol for Cervical Preparation Prior to Procedural Abortion at 12 to 16 Weeks' Gestation in an Academic Medical Center: a Randomized Controlled Pilot Trial

Quick Facts

Study Start:2024-10-31
Study Completion:2026-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06502158

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 45 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * English or Spanish-speaking
  2. * Capacity to consent
  3. * Seeking induced abortion of a singleton pregnancy
  4. * Between 12 weeks, 0 days and 16 weeks, 6 days (based on age at day of surgery)
  1. * History of more than one prior Cesarean delivery
  2. * Sonographic evidence of placenta previa
  3. * Sonographic concern for morbidly adherent placenta
  4. * Prior obstetric hemorrhage requiring transfusion
  5. * Obstructive cervical or lower uterine segment fibroid
  6. * Current therapeutic anticoagulation use
  7. * Cerclage in situ
  8. * History of more than one prior cervical excisional procedure
  9. * BMI greater than 45 kg/m\^2

Contacts and Locations

Study Contact

Laura Fletcher, MD, MPH
CONTACT
516-587-3297
lfletcher@montefiore.org
Antoinette Danvers, MD, MSCR, MBA
CONTACT
718-405-8260
adanvers@montefiore.org

Principal Investigator

Antoinette Danvers, MD, MSCR, MBA
PRINCIPAL_INVESTIGATOR
Montefiore Medical Center

Study Locations (Sites)

Montefiore Medical Center
Bronx, New York, 10467
United States

Collaborators and Investigators

Sponsor: Montefiore Medical Center

  • Antoinette Danvers, MD, MSCR, MBA, PRINCIPAL_INVESTIGATOR, Montefiore Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-10-31
Study Completion Date2026-10

Study Record Updates

Study Start Date2024-10-31
Study Completion Date2026-10

Terms related to this study

Keywords Provided by Researchers

  • Procedural Abortion
  • Surgical Abortion
  • Abortion, First Trimester
  • Cervical Dilators

Additional Relevant MeSH Terms

  • Cervical Preparation