RECRUITING

The Influence of Sleep on Cardiovascular Outcomes

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to identify the effects of sleep regularity on cardiovascular regulatory mechanisms. The investigators are hoping to discover if improving the regularity of sleep timing will improve metabolic and vascular health markers. The protocol is a 12-week prospective cohort study that includes both field and in-laboratory data collection in ostensibly healthy male and female adults, aged 18-40years.

Official Title

Determining the Influence of Sleep on Cardiovascular Outcomes

Quick Facts

Study Start:2024-07-01
Study Completion:2025-09-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06535178

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 40 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * No history of drug or alcohol dependency.
  2. * Must be current non-smokers, and are required to have a history of less than 5 pack years of smoking.
  3. * No history of working irregular day and night hours, regular night work, or rotating shift work for the 1 year prior to the study. In addition to this, individuals must not have traveled across more than 1 time zone during the 3 months prior to the study.
  4. * Chronobiologic and sleep disorders.
  5. * Diseases of the cardiovascular system.
  6. * Hypertension. Individuals will be allowed to be normotensive (resting systolic blood pressure of \<140/90 mmHg, measured on more than one occasion) or uncomplicated stage 1 hypertension (systolic BP between 140 and 159 mmHg or a diastolic BP between 90 and 99 mmHg).
  7. * Disorders of the respiratory system.
  8. * Pre-diabetes/Diabetes. For participants who have self-reported pre-diabetes/diabetes.
  9. * Disorders of the kidney and urinary tract.
  10. * Infectious diseases.
  11. * Disorders of the gastrointestinal system.
  12. * Disorders of the immune system.
  13. * Disorders of the hematopoietic system.
  14. * Neoplastic diseases.
  15. * Endocrine and metabolic diseases.
  16. * Neurologic disorders.
  17. * Must not be participating in another research study that would influence their safe participation in the study.

Contacts and Locations

Study Contact

Andrew W McHill, PhD
CONTACT
(503) 494 - 2594
mchill@ohsu.edu
Brooke M Shafer
CONTACT
(503) 494 - 0670
shaferb@ohsu.edu

Principal Investigator

Andrew W McHill, PhD
PRINCIPAL_INVESTIGATOR
Oregon Health and Science University

Study Locations (Sites)

Oregon Health & Science University
Portland, Oregon, 97239
United States

Collaborators and Investigators

Sponsor: Oregon Health and Science University

  • Andrew W McHill, PhD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-07-01
Study Completion Date2025-09-30

Study Record Updates

Study Start Date2024-07-01
Study Completion Date2025-09-30

Terms related to this study

Keywords Provided by Researchers

  • Circadian Rhythm
  • Cardiometabolic Health
  • Vascular Health

Additional Relevant MeSH Terms

  • Circadian Rhythm
  • Cardiometabolic Health
  • Vascular Health