The Influence of Sleep on Cardiovascular Outcomes

Description

The goal of this study is to identify the effects of sleep regularity on cardiovascular regulatory mechanisms. The investigators are hoping to discover if improving the regularity of sleep timing will improve metabolic and vascular health markers. The protocol is a 12-week prospective cohort study that includes both field and in-laboratory data collection in ostensibly healthy male and female adults, aged 18-40years.

Conditions

Circadian Rhythm, Cardiometabolic Health, Vascular Health

Talk to us

Study Overview

On this page

Study Details

Study overview

The goal of this study is to identify the effects of sleep regularity on cardiovascular regulatory mechanisms. The investigators are hoping to discover if improving the regularity of sleep timing will improve metabolic and vascular health markers. The protocol is a 12-week prospective cohort study that includes both field and in-laboratory data collection in ostensibly healthy male and female adults, aged 18-40years.

Determining the Influence of Sleep on Cardiovascular Outcomes

The Influence of Sleep on Cardiovascular Outcomes

Condition
Circadian Rhythm
Intervention / Treatment

-

Contacts and Locations

Portland

Oregon Health & Science University, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * No history of drug or alcohol dependency.
  • * Must be current non-smokers, and are required to have a history of less than 5 pack years of smoking.
  • * No history of working irregular day and night hours, regular night work, or rotating shift work for the 1 year prior to the study. In addition to this, individuals must not have traveled across more than 1 time zone during the 3 months prior to the study.
  • * Chronobiologic and sleep disorders.
  • * Diseases of the cardiovascular system.
  • * Hypertension. Individuals will be allowed to be normotensive (resting systolic blood pressure of \<140/90 mmHg, measured on more than one occasion) or uncomplicated stage 1 hypertension (systolic BP between 140 and 159 mmHg or a diastolic BP between 90 and 99 mmHg).
  • * Disorders of the respiratory system.
  • * Pre-diabetes/Diabetes. For participants who have self-reported pre-diabetes/diabetes.
  • * Disorders of the kidney and urinary tract.
  • * Infectious diseases.
  • * Disorders of the gastrointestinal system.
  • * Disorders of the immune system.
  • * Disorders of the hematopoietic system.
  • * Neoplastic diseases.
  • * Endocrine and metabolic diseases.
  • * Neurologic disorders.
  • * Must not be participating in another research study that would influence their safe participation in the study.

Ages Eligible for Study

18 Years to 40 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Oregon Health and Science University,

Andrew W McHill, PhD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

2025-09-30