RECRUITING

NAD+ Oral Supplement Pilot Intervention in Adult Females

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to learn if Nicotinamide adenine dinucleotide (NAD+) can influence cognition and biomarkers in healthy, cognitively intact women who identify as Latina and are between the ages of 40-80. The main questions it aims to answer are: Will executive function change in response to NAD+? Will inflammatory markers and serum indicators of neurodegeneration change in response to NAD+? Researchers will compare individuals receiving the NAD+ to see if the results differ from those receiving the placebo. Participants will: Complete an online questionnaire, Visit the lab for computerized cognitive testing and a blood draw, Take NAD+ or a placebo every day for 4 weeks, Visit the lab for computerized cognitive testing and a blood draw

Official Title

NAD+ Oral Supplement Pilot Intervention in Adult Females

Quick Facts

Study Start:2024-12-01
Study Completion:2025-05-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06579209

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:40 Years to 80 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Identify as Latina, have three or more adverse childhood experiences, and a BMI of 18.5 or above
  1. * Those who are taking hormone medication, pregnant or breastfeeding

Contacts and Locations

Study Contact

Cindy E Tsotsoros, PhD
CONTACT
(401) 874-7425
cindy-tsotsoros@uri.edu

Study Locations (Sites)

University of Rhode Island
Kingston, Rhode Island, 02881
United States
Independence Square, University of Rhode Island
Pawtucket, Rhode Island, 02860
United States

Collaborators and Investigators

Sponsor: University of Rhode Island

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-01
Study Completion Date2025-05-01

Study Record Updates

Study Start Date2024-12-01
Study Completion Date2025-05-01

Terms related to this study

Additional Relevant MeSH Terms

  • Cognitive Change
  • Inflammation
  • Neurodegenerative Diseases