NAD+ Oral Supplement Pilot Intervention in Adult Females

Description

The goal of this clinical trial is to learn if Nicotinamide adenine dinucleotide (NAD+) can influence cognition and biomarkers in healthy, cognitively intact women who identify as Latina and are between the ages of 40-80. The main questions it aims to answer are: Will executive function change in response to NAD+? Will inflammatory markers and serum indicators of neurodegeneration change in response to NAD+? Researchers will compare individuals receiving the NAD+ to see if the results differ from those receiving the placebo. Participants will: Complete an online questionnaire, Visit the lab for computerized cognitive testing and a blood draw, Take NAD+ or a placebo every day for 4 weeks, Visit the lab for computerized cognitive testing and a blood draw

Conditions

Cognitive Change, Inflammation, Neurodegenerative Diseases

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Study Overview

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Study Details

Study overview

The goal of this clinical trial is to learn if Nicotinamide adenine dinucleotide (NAD+) can influence cognition and biomarkers in healthy, cognitively intact women who identify as Latina and are between the ages of 40-80. The main questions it aims to answer are: Will executive function change in response to NAD+? Will inflammatory markers and serum indicators of neurodegeneration change in response to NAD+? Researchers will compare individuals receiving the NAD+ to see if the results differ from those receiving the placebo. Participants will: Complete an online questionnaire, Visit the lab for computerized cognitive testing and a blood draw, Take NAD+ or a placebo every day for 4 weeks, Visit the lab for computerized cognitive testing and a blood draw

NAD+ Oral Supplement Pilot Intervention in Adult Females

NAD+ Oral Supplement Pilot Intervention in Adult Females

Condition
Cognitive Change
Intervention / Treatment

-

Contacts and Locations

Kingston

University of Rhode Island, Kingston, Rhode Island, United States, 02881

Pawtucket

Independence Square, University of Rhode Island, Pawtucket, Rhode Island, United States, 02860

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Identify as Latina, have three or more adverse childhood experiences, and a BMI of 18.5 or above
  • * Those who are taking hormone medication, pregnant or breastfeeding

Ages Eligible for Study

40 Years to 80 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Rhode Island,

Study Record Dates

2025-05-01