RECRUITING

Manual Versus AI-Assisted Clinical Trial Screening Using Large-Language Models

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

A prospective randomized controlled trial comparing manual review and AI screening for patient eligibility determination and enrollments. A structured query will identify potentially eligible patients from the Mass General Brigham Electronic Data Warehouse (EDW), who will then be randomized into either the manual review arm or the AI-assisted review arm.

Official Title

Manual Versus AI-Assisted Clinical Trial Screening Using Large-Language Models

Quick Facts

Study Start:2024-03-04
Study Completion:2024-09-13
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06588452

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Documented diagnosis of heart failure (e.g., ICD-9 codes 428 ICD-10 codes I50 or Problem list in the electronic health record)
  2. * Most recent left ventricular ejection fraction (LVEF) assessed within the past 24 months
  3. * Seen Mass General Brigham provider within the last 24 months
  1. * LVEF \<50% currently prescribed or intolerant to an evidence-based beta-blocker, ARNI, MRA, and SGLT2i at least 50% goal dose
  2. * LVEF\>50% currently prescribed or intolerant to SGLT2i
  3. * Systolic blood pressure (SBP) \<90 mmHg at last measure

Contacts and Locations

Study Contact

Ozan Unlu, MD
CONTACT
617-732-7144
ounlu@bwh.harvard.edu
Alexander J Blood, MD
CONTACT
617-732-7144
ablood3@mgb.org

Principal Investigator

Benjamin M Scirica, MD, MSc
STUDY_CHAIR
Brigham and Women's Hospital

Study Locations (Sites)

Brigham and Women's Hospital
Boston, Massachusetts, 02115
United States

Collaborators and Investigators

Sponsor: Brigham and Women's Hospital

  • Benjamin M Scirica, MD, MSc, STUDY_CHAIR, Brigham and Women's Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-03-04
Study Completion Date2024-09-13

Study Record Updates

Study Start Date2024-03-04
Study Completion Date2024-09-13

Terms related to this study

Additional Relevant MeSH Terms

  • Comparing Manual and AI Patient Screening in Heart Failure