RECRUITING

Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators are conducting this research study to find better ways of treating pain following knee surgery. There is a standard (accepted) approach, which involves injection of numbing medication into the area around the participant surgical incision. The investigators hope to discover if providing numbing medication to a nerve that controls pain in a larger area of the knee (a nerve block), might be better at post-operative pain control.

Official Title

Genicular Nerve Block for Analgesia After Open Reduction Internal Fixation of Tibial Plateau Fractures: A Prospective, Randomized Controlled Trial

Quick Facts

Study Start:2024-11-01
Study Completion:2026-06-14
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06639503

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * Subjects younger than 18
  2. * Polytraumatized Subjects
  3. * Subjects with pathologic fractures
  4. * Subjects with tibial plateau fractures treated nonoperatively
  5. * Subjects with tibial plateau fractures treated operatively but with re-operations at the same site
  6. * Subjects with open fractures
  7. * Subjects with fracture-dislocations
  8. * Subjects with active or history of anxiety
  9. * Subjects with visual analog scale anxiety score ≥ 7 measured preoperatively
  10. * Subjects with chronic pain syndromes
  11. * Subjects with chronic opioid use
  12. * Subjects with illicit drug use disorder
  13. * Subjects with alcohol abuse disorder
  14. * Subjects with kidney disease precluding use of ketorolac
  15. * Subjects with liver disease precluding the use of acetaminophen
  16. * Subjects with allergy to acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), opiates or local anesthesia
  17. * Subjects with inability to provide a visual analog scale score postoperatively
  18. * Subjects with contraindications to receiving peripheral nerve blocks, including relevant neurologic deficits, active infection at sites of injections - re-operation at the same site

Contacts and Locations

Study Contact

Anthony Christiano, MD
CONTACT
773-834-3531
anthony.christiano@bsd.uchicago.edu

Principal Investigator

Anthony Christiano, MD
PRINCIPAL_INVESTIGATOR
University of Chicago

Study Locations (Sites)

University of Chicago
Chicago, Illinois, 60637
United States

Collaborators and Investigators

Sponsor: University of Chicago

  • Anthony Christiano, MD, PRINCIPAL_INVESTIGATOR, University of Chicago

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-11-01
Study Completion Date2026-06-14

Study Record Updates

Study Start Date2024-11-01
Study Completion Date2026-06-14

Terms related to this study

Keywords Provided by Researchers

  • peri-incisional local anesthesia
  • genicular nerve block
  • Tibial Plateau Fractures
  • open reduction internal fixation

Additional Relevant MeSH Terms

  • Tibial Plateau Fractures