Study Overview
This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.
Description
The objective of the NeoPlaTT trial is to test whether, among extremely preterm infants born at 23 0/7 to 26 6/7 weeks' gestation, a lower platelet transfusion threshold, compared to a higher threshold, improves survival without major or severe bleeding up to 40 0/7 weeks' postmenstrual age (PMA).
Official Title
Neonatal Platelet Transfusion Threshold Trial
Quick Facts
Study Start:2025-06-01
Study Completion:2031-04-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
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Contacts and Locations
Study Locations (Sites)
University of Alabama at Birmingham
Birmingham, Alabama, 35233
United States
Stanford University
Palo Alto, California, 94304
United States
Sharp Mary Birch Hospital for Women & Newborns
San Diego, California, 92123
United States
University of Colorado
Aurora, Colorado, 80045
United States
Emory University
Atlanta, Georgia, 30303
United States
Northwestern Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611
United States
University of Iowa
Iowa City, Iowa, 52242
United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215
United States
University of New Mexico
Albuquerque, New Mexico, 87131
United States
University of Rochester
Rochester, New York, 14642
United States
Duke University
Durham, North Carolina, 27710
United States
Cincinnati Children's Medical Center
Cincinnati, Ohio, 45267
United States
Case Western Reserve University, Rainbow Babies and Children's Hospital
Cleveland, Ohio, 44106
United States
Nationwide Children's Hospital
Columbus, Ohio, 43205
United States
University of Pennsylvania
Philadelphia, Pennsylvania, 19104
United States
Vanderbilt University
Nashville, Tennessee, 37232
United States
University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, 75235
United States
University of Texas Health Science Center at Houston
Houston, Texas, 77030
United States
Pediatrix Medical Group
San Antonio, Texas, 78229
United States
University of Utah
Salt Lake City, Utah, 84108
United States
Collaborators and Investigators
Sponsor: NICHD Neonatal Research Network
- Ravi M Patel, MD, PRINCIPAL_INVESTIGATOR, Emory University
Study Record Dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
Study Start Date2025-06-01
Study Completion Date2031-04-30
Study Record Updates
Study Start Date2025-06-01
Study Completion Date2031-04-30
Terms related to this study
Keywords Provided by Researchers
- platelet transfusion
- neonatal
- thrombosis
Additional Relevant MeSH Terms
- Thrombocytopenia
- Neonatal
- Platelet Transfusion
- Infant, Newborn, Diseases
- Infant, Extremely Low Birth Weight
- Infant, Small for Gestational Age
- Thrombosis