RECRUITING

Gonadal Tissue Cryopreservation for Fertility Preservation in Children with a Disorder of Sex Development

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer). This study involves the storage of gonadal tissue that is being removed for medical reasons (e.g. prevention of cancer development). It includes the processing and freezing of this gonadal tissue, hopefully for potential future use. The tissue will then be stored long-term until the child wishes to try to use the tissue.

Official Title

Gonadal Tissue Cryopreservation for Fertility Preservation in Children with a Disorder of Sex Development

Quick Facts

Study Start:2018-04-04
Study Completion:2035-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06692049

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 30 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Individual \< 30 years of age
  2. * Children diagnosed with a disorder of sex development who have any risk for malignancy in their gonadal tissue or will have their gonads removed for another clinical indication
  1. * Pregnant children
  2. * Patients likely to retain inherent fertility and reproductive function
  3. * Children deemed high risk for perioperative complications
  4. * Patients 12-18 unable to provide assent (i.e. significant psychiatric problems/cognitive delay)
  5. * Patients 18 and older unable to provide consent (i.e. significant psychiatric problems/cognitive delay)

Contacts and Locations

Study Contact

Sara Reyes
CONTACT
3122274145
FertilityPreservation@luriechildrens.org

Principal Investigator

Erin Rowell, MD
PRINCIPAL_INVESTIGATOR
Ann & Robert H Lurie Children's Hospital of Chicago

Study Locations (Sites)

Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611
United States

Collaborators and Investigators

Sponsor: Erin Rowell

  • Erin Rowell, MD, PRINCIPAL_INVESTIGATOR, Ann & Robert H Lurie Children's Hospital of Chicago

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-04-04
Study Completion Date2035-12-31

Study Record Updates

Study Start Date2018-04-04
Study Completion Date2035-12-31

Terms related to this study

Keywords Provided by Researchers

  • DSD
  • GTC
  • Gonadectomy
  • Cryopreservation
  • Fertility Preservation

Additional Relevant MeSH Terms

  • DSD, 46,XY
  • DSD, Ovotesticular
  • DSD, Sex Chromosome
  • Disorders of Sex Development
  • Disorder of Sex Development, 46,XY
  • Disorder of Sex Development, 46,Xy, Cbx2-Related