Gonadal Tissue Cryopreservation for Fertility Preservation in Children with a Disorder of Sex Development

Description

The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer). This study involves the storage of gonadal tissue that is being removed for medical reasons (e.g. prevention of cancer development). It includes the processing and freezing of this gonadal tissue, hopefully for potential future use. The tissue will then be stored long-term until the child wishes to try to use the tissue.

Conditions

DSD, 46,XY, DSD, Ovotesticular, DSD, Sex Chromosome, Disorders of Sex Development, Disorder of Sex Development, 46,XY, Disorder of Sex Development, 46,Xy, Cbx2-Related

Study Overview

Study Details

Study overview

The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer). This study involves the storage of gonadal tissue that is being removed for medical reasons (e.g. prevention of cancer development). It includes the processing and freezing of this gonadal tissue, hopefully for potential future use. The tissue will then be stored long-term until the child wishes to try to use the tissue.

Gonadal Tissue Cryopreservation for Fertility Preservation in Children with a Disorder of Sex Development

Gonadal Tissue Cryopreservation for Fertility Preservation in Children with a Disorder of Sex Development

Condition
DSD, 46,XY
Intervention / Treatment

-

Contacts and Locations

Chicago

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States, 60611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Individual \< 30 years of age
  • * Children diagnosed with a disorder of sex development who have any risk for malignancy in their gonadal tissue or will have their gonads removed for another clinical indication
  • * Pregnant children
  • * Patients likely to retain inherent fertility and reproductive function
  • * Children deemed high risk for perioperative complications
  • * Patients 12-18 unable to provide assent (i.e. significant psychiatric problems/cognitive delay)
  • * Patients 18 and older unable to provide consent (i.e. significant psychiatric problems/cognitive delay)

Ages Eligible for Study

to 30 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Erin Rowell,

Erin Rowell, MD, PRINCIPAL_INVESTIGATOR, Ann & Robert H Lurie Children's Hospital of Chicago

Study Record Dates

2035-12-31