RECRUITING

APPI-Cost Trial for Perforated Appendicitis

Description

The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis, to investigate barriers and facilitators to future implementation of PVI irrigation, and to collect costs and clinical and patient-reported outcomes among patients with non-perforated appendicitis.

Study Overview

Study Details

Study overview

The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis, to investigate barriers and facilitators to future implementation of PVI irrigation, and to collect costs and clinical and patient-reported outcomes among patients with non-perforated appendicitis.

The APPI-Cost Trial: Cost Assessment of Povidone-Iodine Irrigation for Prevention of Intra-abdominal Abscess in Perforated Appendicitis

APPI-Cost Trial for Perforated Appendicitis

Condition
Perforated Appendicitis
Intervention / Treatment

-

Contacts and Locations

Houston

The University of Texas Health Science Center at Houston, Houston, Texas, United States, 77030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Plan to undergo appendectomy for acute appendicitis
  • * Preoperative hemodynamic instability requiring ongoing infusion of vasopressors
  • * Allergy to iodine
  • * Uncontrolled hyper- or hypothyroidism
  • * Renal dysfunction
  • * Pregnant or breastfeeding
  • * Primary language neither English nor Spanish
  • * Lack of functioning telephone or email account
  • * Incarcerated or in police custody

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

The University of Texas Health Science Center, Houston,

Dalya Ferguson, MD, MS, PRINCIPAL_INVESTIGATOR, The University of Texas Health Science Center, Houston

Study Record Dates

2027-06-30