RECRUITING

APPI-Cost Trial for Perforated Appendicitis

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis, to investigate barriers and facilitators to future implementation of PVI irrigation, and to collect costs and clinical and patient-reported outcomes among patients with non-perforated appendicitis.

Official Title

The APPI-Cost Trial: Cost Assessment of Povidone-Iodine Irrigation for Prevention of Intra-abdominal Abscess in Perforated Appendicitis

Quick Facts

Study Start:2025-04-07
Study Completion:2027-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06705842

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Plan to undergo appendectomy for acute appendicitis
  1. * Preoperative hemodynamic instability requiring ongoing infusion of vasopressors
  2. * Allergy to iodine
  3. * Uncontrolled hyper- or hypothyroidism
  4. * Renal dysfunction
  5. * Pregnant or breastfeeding
  6. * Primary language neither English nor Spanish
  7. * Lack of functioning telephone or email account
  8. * Incarcerated or in police custody

Contacts and Locations

Study Contact

Dalya M Ferguson, MD, MS
CONTACT
(713) 566-5098
Dalya.M.Ferguson@uth.tmc.edu
Debbie Nguyen
CONTACT
(713) 566-5098
Debbie.F.Lew@uth.tmc.edu

Principal Investigator

Dalya Ferguson, MD, MS
PRINCIPAL_INVESTIGATOR
The University of Texas Health Science Center, Houston

Study Locations (Sites)

The University of Texas Health Science Center at Houston
Houston, Texas, 77030
United States

Collaborators and Investigators

Sponsor: The University of Texas Health Science Center, Houston

  • Dalya Ferguson, MD, MS, PRINCIPAL_INVESTIGATOR, The University of Texas Health Science Center, Houston

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04-07
Study Completion Date2027-06-30

Study Record Updates

Study Start Date2025-04-07
Study Completion Date2027-06-30

Terms related to this study

Keywords Provided by Researchers

  • Perforated Appendicitis
  • Povidone Iodine
  • Cost effectiveness
  • Intra-abdominal abscess
  • Appendectomy
  • Implementation science

Additional Relevant MeSH Terms

  • Perforated Appendicitis