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Omega-3 Fatty Acids and Subconcussive Head Impacts

Description

The purpose of the proposed double-blind, randomized placebo-controlled trial is to understand how supplementation with fish oil \[docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)\] promote brain health against soccer heading. The study involves taking DHA+EPA or placebo, questionnaires, blood draws, brain imaging, tests to evaluate heart function, and soccer headings.

Conditions

Subconcussive Head ImpactOmega-3 Fatty Acids
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Related Conditions:

Subconcussive Head ImpactOmega-3 Fatty Acids

Study Overview

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Study Details

Study overview

The purpose of the proposed double-blind, randomized placebo-controlled trial is to understand how supplementation with fish oil \[docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)\] promote brain health against soccer heading. The study involves taking DHA+EPA or placebo, questionnaires, blood draws, brain imaging, tests to evaluate heart function, and soccer headings.

Mechanistic Investigation of Omega-3 Fatty Acids Pretreatment Effects on Subconcussive Brain Injury

Omega-3 Fatty Acids and Subconcussive Head Impacts

Condition
Subconcussive Head Impact
Intervention / Treatment

-

Contacts and Locations

Bloomington

Indiana University School of Public Health, Bloomington, Indiana, United States, 47405

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Between age 18-30
  • * Current or former soccer player
  • * At least 5 years of soccer heading experience
  • * Have internet access
  • * Willing to commit to avoid any sport activity that purposefully uses one's head to maneuver during the study period (American football, ice-hockey, rugby, wrestling, and soccer heading).
  • * Any head or neck injury within 6 months before the study
  • * Implanted metal/magnetic devices (e.g., orthodontic braces
  • * Diagnosed autonomic or cardiovascular diseases (e.g., hypertension)
  • * Consuming oily fish (2 servings or more/month: salmon, bluefin, swordfish, anchovies)
  • * Allergy to fish or shellfish
  • * Consuming omega-3 FA supplements including plant-based (e.g., flaxseed) in the past 3 months.
  • * Pregnancy

Ages Eligible for Study

18 Years to 30 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Indiana University,

Study Record Dates

2029-05-31