RECRUITING

Omega-3 Fatty Acids and Subconcussive Head Impacts

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the proposed double-blind, randomized placebo-controlled trial is to understand how supplementation with fish oil \[docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)\] promote brain health against soccer heading. The study involves taking DHA+EPA or placebo, questionnaires, blood draws, brain imaging, tests to evaluate heart function, and soccer headings.

Official Title

Mechanistic Investigation of Omega-3 Fatty Acids Pretreatment Effects on Subconcussive Brain Injury

Quick Facts

Study Start:2025-02-28
Study Completion:2029-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06736925

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 30 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Between age 18-30
  2. * Current or former soccer player
  3. * At least 5 years of soccer heading experience
  4. * Have internet access
  5. * Willing to commit to avoid any sport activity that purposefully uses one's head to maneuver during the study period (American football, ice-hockey, rugby, wrestling, and soccer heading).
  1. * Any head or neck injury within 6 months before the study
  2. * Implanted metal/magnetic devices (e.g., orthodontic braces
  3. * Diagnosed autonomic or cardiovascular diseases (e.g., hypertension)
  4. * Consuming oily fish (2 servings or more/month: salmon, bluefin, swordfish, anchovies)
  5. * Allergy to fish or shellfish
  6. * Consuming omega-3 FA supplements including plant-based (e.g., flaxseed) in the past 3 months.
  7. * Pregnancy

Contacts and Locations

Study Contact

Kei Kawata
CONTACT
812-855-5244
kkawata@indiana.edu

Study Locations (Sites)

Indiana University School of Public Health
Bloomington, Indiana, 47405
United States

Collaborators and Investigators

Sponsor: Indiana University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-28
Study Completion Date2029-05-31

Study Record Updates

Study Start Date2025-02-28
Study Completion Date2029-05-31

Terms related to this study

Keywords Provided by Researchers

  • Subconcussive brain injury
  • TBI
  • Soccer heading
  • Omega-3 fatty acids

Additional Relevant MeSH Terms

  • Subconcussive Head Impact
  • Omega-3 Fatty Acids