RECRUITING

Phosphatidylethanol and Other Ethanol Consumption Markers

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is intended to help the investigators understand how a biomarker found in the blood may be used to better identify the quantity and different patterns of alcohol use. The investigators hope that the results of this study will help identify the uses of alcohol-use markers in the blood in future alcohol prevention and treatment programs. It is hoped that the information learned from this study will benefit other people in the future. The study participants will come into the lab and will (1) consume alcohol in the lab designed to produce a peak blood alcohol concentration of 0.06% and have blood collected over 6 hours followed by abstinence for 10 days to give a small blood sample 4 times and (2) to give a small amount of blood 5 times within 28 days (naturalistic drinking) and provide answers about alcohol use.

Official Title

Phosphatidylethanol and Other Ethanol Consumption Markers

Quick Facts

Study Start:2025-02
Study Completion:2029-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06747364

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. are ≥ 21 years old;
  2. 2. are height and weight proportionate (body mass index 18-30); and
  3. 3. report drinking on \> 1 days in the last month, with at least one day equal to at least achieving \~0.06% BAC.
  1. 1. have significant current or predicted alcohol withdrawal symptoms (CIWA-AR scores ≥ 10);
  2. 2. are currently in alcohol treatment;
  3. 3. have substance use disorder (except nicotine, and/or caffeine);
  4. 4. have a medical condition that would contraindicate participation (a positive urine pregnancy test, self-reported scheduled surgery or liver disease);
  5. 5. are currently breast feeding;
  6. 6. have a presence of a DSM-5 psychiatric disorder with symptoms of psychosis and/or delirium; or
  7. 7. are unable to comprehend the informed consent process or study instructions.

Contacts and Locations

Study Contact

Nathalie Hill-Kapturczak, PhD
CONTACT
210-567-2725
Hillkapturcz@uthscsa.edu
Donald Dougherty, PhD
CONTACT
940-565-2649
Donald.Dougherty@unt.edu

Principal Investigator

Nathalie Hill-Kapturczak, PhD
PRINCIPAL_INVESTIGATOR
The University of Texas Health Science Center at San Antonio
Donald Dougherty, PhD
PRINCIPAL_INVESTIGATOR
University of North Texas Health Science Center

Study Locations (Sites)

University of North Texas
Denton, Texas, 76201
United States
University of Texas Health Science Center San Antonio
San Antonio, Texas, 78229
United States

Collaborators and Investigators

Sponsor: The University of Texas Health Science Center at San Antonio

  • Nathalie Hill-Kapturczak, PhD, PRINCIPAL_INVESTIGATOR, The University of Texas Health Science Center at San Antonio
  • Donald Dougherty, PhD, PRINCIPAL_INVESTIGATOR, University of North Texas Health Science Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02
Study Completion Date2029-06

Study Record Updates

Study Start Date2025-02
Study Completion Date2029-06

Terms related to this study

Keywords Provided by Researchers

  • Healthy adult
  • Light, moderate and heavy drinkers

Additional Relevant MeSH Terms

  • Healthy Volunteer
  • Alcohol Consumption