RECRUITING

Vancomycin Reduction Practices (VRP) in the NICU

Description

This multi-center, cluster randomized study aimed at improving implementation of vancomycin reducing practices (VRP) in neonatal intensive care units (NICUs). Sites will be recruited and randomized to receive either external facilitation or no external facilitation to assess the effect on center-level fidelity to the core components of VRP implementation. Interventions available to both study arms are directed at hospital staff and includes identification of local champions, educational outreach, unit-level audit \& feedback, and use of a clinical decision support tool.

Study Overview

Study Details

Study overview

This multi-center, cluster randomized study aimed at improving implementation of vancomycin reducing practices (VRP) in neonatal intensive care units (NICUs). Sites will be recruited and randomized to receive either external facilitation or no external facilitation to assess the effect on center-level fidelity to the core components of VRP implementation. Interventions available to both study arms are directed at hospital staff and includes identification of local champions, educational outreach, unit-level audit \& feedback, and use of a clinical decision support tool.

Implementing Vancomycin Reducing Practices (VRP) in Preterm Infants

Vancomycin Reduction Practices (VRP) in the NICU

Condition
Antibiotic Stewardship
Intervention / Treatment

-

Contacts and Locations

Modesto

Kaiser Permanente Modesto Medical Center, Modesto, California, United States, 95356

Oakland

Kaiser Permanente East Bay - Oakland Medical Center, Oakland, California, United States, 94611

Roseville

Kaiser Permanente Roseville Medical Center, Roseville, California, United States, 95661

San Francisco

Kaiser Permanente San Francisco Medical Center, San Francisco, California, United States, 94115

San Leandro

Kaiser Permanente San Leandro Medical Center, San Leandro, California, United States, 94577

Santa Clara

Kaiser Permanente Santa Clara Medical Center, Santa Clara, California, United States, 95051

Walnut Creek

Kaiser Permanente Walnut Creek Medical Center, Walnut Creek, California, United States, 94596

Plainsboro

Medical Center of Princeton, Plainsboro, New Jersey, United States, 08536

Voorhees

Virtua Voorhees, Voorhees, New Jersey, United States, 08043

Lancaster

Lancaster General Hospital, Lancaster, Pennsylvania, United States, 17602

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Level III NICU
  • * Affiliated with Kaiser Permanente Northern California (KPNC) or Children's Hospital of Philadelphia Newborn Care Network (CNBCN)
  • * Recruited by study team
  • * Site not recruited for the study

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Children's Hospital of Philadelphia,

Sagori Mukhopadhyay, MD, MMSc, PRINCIPAL_INVESTIGATOR, Children's Hospital of Philadelphia

Study Record Dates

2027-09