RECRUITING

TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD

Description

The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable sensors, and 2) to explore whether two different rehabilitation intervention can reduce FOG and improve daily life mobility in people with FOG sufficiently to justify a clinical trial. Participants will: * Be randomly assigned to one of two intervention groups (turning-focused agility exercise or strength-based exercise) * Have one-on-one training sessions three times per week for 6 weeks * Perform in-lab assessments before beginning and after completing the study intervention * Use wearable mobility sensors during daily life to measure their walking and balance

Study Overview

Study Details

Study overview

The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable sensors, and 2) to explore whether two different rehabilitation intervention can reduce FOG and improve daily life mobility in people with FOG sufficiently to justify a clinical trial. Participants will: * Be randomly assigned to one of two intervention groups (turning-focused agility exercise or strength-based exercise) * Have one-on-one training sessions three times per week for 6 weeks * Perform in-lab assessments before beginning and after completing the study intervention * Use wearable mobility sensors during daily life to measure their walking and balance

TURN-IT FOG: A Novel Intervention to Improve Turning in People With PD and Freezing of Gait

TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD

Condition
Parkinson Disease
Intervention / Treatment

-

Contacts and Locations

Tempe

Arizona State University, Tempe, Arizona, United States, 85281

Portland

Oregon Health and Science University, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * diagnosis of idiopathic PD from movement disorders neurologist with the United Kingdom Brain Bank criteria of bradykinesia with one or more of the following - rest tremor, rigidity, and balance problems not from visual, vestibular, cerebellar or proprioceptive conditions
  • * reporting FOG in the New Freezing of Gait questionnaire (N-FOGQ)
  • * Hoehn \& Yahr stages II-IV
  • * ages 50-80 years old
  • * cognitive ability sufficient to participate in testing procedures and exercise classes
  • * be willing and able to participate in exercise intervention 3x/week for 6 weeks
  • * Major musculoskeletal or neurological disorders, structural brain disease, epilepsy, acute illness or health history, other than PD, significantly affecting gait and turning (i.e., musculoskeletal disorder, vestibular problem, head injury, stroke, cardiac disease)
  • * medical condition or medications that precludes moderate-intensity exercise
  • * Montreal Cognitive Assessment (MoCA) ≤21 or inability to follow directions
  • * excessive use of alcohol or recreational drugs
  • * recent change in medication
  • * inability to stand and walk for 2 minutes without an assistive device

Ages Eligible for Study

50 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Oregon Health and Science University,

Martina Mancini, PhD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

2027-06-30