RECRUITING

Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

Description

This study seeks to identify if it is feasible to stop Luteinizing Hormone-Releasing Hormone (LHRH) Agonist Therapy in elderly men with prostate cancer. We hypothesize that elderly prostate cancer patients on long term androgen ablation with LHRH agonists will be permanently castrated and do not require ongoing LHRH agonist therapy. Participants will be monitored by testosterone testing throughout study.

Study Overview

Study Details

Study overview

This study seeks to identify if it is feasible to stop Luteinizing Hormone-Releasing Hormone (LHRH) Agonist Therapy in elderly men with prostate cancer. We hypothesize that elderly prostate cancer patients on long term androgen ablation with LHRH agonists will be permanently castrated and do not require ongoing LHRH agonist therapy. Participants will be monitored by testosterone testing throughout study.

A Feasibility Trial of LHRH Agonist Discontinuation in Elderly Prostate Cancer Patients

Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

Condition
Elderly
Intervention / Treatment

-

Contacts and Locations

Chicago

The University of Illinois at Chicago (UIC), Chicago, Illinois, United States, 60607

Chicago

UChicago Medicine Comprehensive Cancer Center, Chicago, Illinois, United States, 60637

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Prostate cancer with \>3 years of LHRH agonist therapy.
  • * Age ≥70 years.
  • * ECOG performance status ≤2
  • * Baseline testosterone of \< 20 ng/ml
  • * No prior chemotherapy or Lu-PSMA (unless survival predictions are favorable).
  • * Ability to understand and sign informed consent.
  • * none

Ages Eligible for Study

70 Years to

Sexes Eligible for Study

MALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Chicago,

Nabiel Mir, MD, STUDY_CHAIR, University of Chicago

Study Record Dates

2027-06