RECRUITING

Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study seeks to identify if it is feasible to stop Luteinizing Hormone-Releasing Hormone (LHRH) Agonist Therapy in elderly men with prostate cancer. We hypothesize that elderly prostate cancer patients on long term androgen ablation with LHRH agonists will be permanently castrated and do not require ongoing LHRH agonist therapy. Participants will be monitored by testosterone testing throughout study.

Official Title

A Feasibility Trial of LHRH Agonist Discontinuation in Elderly Prostate Cancer Patients

Quick Facts

Study Start:2025-06
Study Completion:2027-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06824818

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:70 Years
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:No
Standard Ages:OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Prostate cancer with \>3 years of LHRH agonist therapy.
  2. * Age ≥70 years.
  3. * ECOG performance status ≤2
  4. * Baseline testosterone of \< 20 ng/ml
  5. * No prior chemotherapy or Lu-PSMA (unless survival predictions are favorable).
  6. * Ability to understand and sign informed consent.
  1. * none

Contacts and Locations

Study Contact

Clinical Trials Intake
CONTACT
1-855-702-8222
cancerclinicaltrials@bsd.uchicago.edu

Principal Investigator

Nabiel Mir, MD
STUDY_CHAIR
University of Chicago

Study Locations (Sites)

The University of Illinois at Chicago (UIC)
Chicago, Illinois, 60607
United States
UChicago Medicine Comprehensive Cancer Center
Chicago, Illinois, 60637
United States

Collaborators and Investigators

Sponsor: University of Chicago

  • Nabiel Mir, MD, STUDY_CHAIR, University of Chicago

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06
Study Completion Date2027-06

Study Record Updates

Study Start Date2025-06
Study Completion Date2027-06

Terms related to this study

Additional Relevant MeSH Terms

  • Elderly
  • Prostate Cancer