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WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)

Description

The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS) intervention initiated 30 days post-surgery improves brain function and thinking. The study does NOT cover any costs associated with bariatric surgery.

Study Overview

Study Details

Study overview

The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS) intervention initiated 30 days post-surgery improves brain function and thinking. The study does NOT cover any costs associated with bariatric surgery.

Obesity and Type 2 Diabetes: Bariatric Surgery Effects on Brain Function -Part 2 (WISE-2B Brain Study)

WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)

Condition
Diabetes
Intervention / Treatment

-

Contacts and Locations

Gainesville

University of Florida - College of Public Health and Health Professions, Gainesville, Florida, United States, 32611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Between age: 20-75 yrs, English speaking, Physically mobile
  • * Body Mass Index (BMI) \>35 kg before surgery
  • * Compatible of MRI Scanning
  • * Willing to give a small blood sample
  • * Capable of providing informed consent
  • * Prior or current neurological disorder
  • * Major psychiatric disturbance
  • * Unstable medical conditions (cancer)
  • * MRI contraindications (claustrophobia, metal implants, waist/torso circumference)

Ages Eligible for Study

20 Years to 75 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Florida,

Eric Porges, PhD, PRINCIPAL_INVESTIGATOR, University of Florida

Study Record Dates

2027-09