RECRUITING

Sickle Cell, Pain and Mediterranean Diet

Description

The goal of this study is to compare pain levels in individuals with Sickle Cell Disease while following the Mediterranean Diet to pain levels while following their usual diet.

Conditions

Sickle CellSickle Cell DiseaseSickle Cell Disease Without CrisisMediterranean Diet
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Related Conditions:

Sickle CellSickle Cell DiseaseSickle Cell Disease Without CrisisMediterranean Diet

Study Overview

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Study Details

Study overview

The goal of this study is to compare pain levels in individuals with Sickle Cell Disease while following the Mediterranean Diet to pain levels while following their usual diet.

Exploring the Mediterranean Diet as A Promising Approach for Alleviating Chronic Pain in Sickle Cell Disease

Sickle Cell, Pain and Mediterranean Diet

Condition
Sickle Cell
Intervention / Treatment

-

Contacts and Locations

Chicago

University of Illinois Chicago, Chicago, Illinois, United States, 60612

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Sickle Cell Disease Diagnosis
  • * Chronic non-vaso-occlusive pain experienced on average ≥ 3 days per week for \> 6 months (based on a response of "Most days," "Every day," or "Some days" and not "Never" to the question "In the past 6 months, how often have you had pain?")
  • * Ability to speak, read, write, and understand English
  • * A Mediterranean Eating Pattern for Americans (MEPA-III) score \<13, indicating that they do not follow a Mediterranean diet.
  • * Having taken systemic antimicrobials (to treat an infection in the previous 4 weeks)
  • * History of colon cancer or inflammatory bowel disease (given potential untoward effects on the gut microbiome)
  • * History of Clostridium difficile infection in the preceding 12 weeks; (4) unable to agree to maintain physical activity at the current level for the duration of the study
  • * Currently following a Mediterranean diet, vegan diet, or dietary restrictions (e.g., religious, food intolerance/allergy) that preclude adoption of a Mediterranean diet
  • * Lack of access to a space to safely store and reheat food items
  • * Living in a facility that provides meals.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Illinois at Chicago,

Study Record Dates

2026-12-01