RECRUITING

Team Science (The Liver Health Study)

Description

Liver damage from alcohol intake and weight-related behaviors is preventable and treatable only through lifestyle changes. This mixed-methods randomized controlled trial compares standard and enhanced approaches to screening, brief intervention, and referral to treatment/prevention (SBIRT/P) to identify and intervene for metabolism- and alcohol-associated liver disease (MetALD). Our multidisciplinary team aims to show that integrating results of noninvasive liver screening with Fibroscan®, a painless ultrasound that measures stiffness and fat in the liver, can optimize our brief intervention. The study population is adults age 21+ who speak Spanish or English from underresourced communities with alcohol- and weight-related risks for MetALD.

Conditions

Steatotic Liver Disease of Mixed Origin (MetALD)
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Related Conditions:

Steatotic Liver Disease of Mixed Origin (MetALD)

Study Overview

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Study Details

Study overview

Liver damage from alcohol intake and weight-related behaviors is preventable and treatable only through lifestyle changes. This mixed-methods randomized controlled trial compares standard and enhanced approaches to screening, brief intervention, and referral to treatment/prevention (SBIRT/P) to identify and intervene for metabolism- and alcohol-associated liver disease (MetALD). Our multidisciplinary team aims to show that integrating results of noninvasive liver screening with Fibroscan®, a painless ultrasound that measures stiffness and fat in the liver, can optimize our brief intervention. The study population is adults age 21+ who speak Spanish or English from underresourced communities with alcohol- and weight-related risks for MetALD.

Team Science to Identify & Intervene on Metabolism- & Alcohol-Associated Liver Disease

Team Science (The Liver Health Study)

Condition
Steatotic Liver Disease of Mixed Origin (MetALD)
Intervention / Treatment

-

Contacts and Locations

Providence

Clinica Esperanza Hope Clinic, Providence, Rhode Island, United States, 02909

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Be at least 21 years of age.
  • * Exceed alcohol intake screening guidelines for MetALD.
  • * Have a Body Mass Index (BMI) \>=25 kg/m2.
  • * Be able to speak and read English or Spanish to provide written informed consent and understand written and oral instructions in English or Spanish.
  • * Pre-existing liver disease or hepatocellular carcinoma or prior liver transplant.
  • * Pre-existing medical conditions that, in the opinion of the investigative team, would interfere with research participation (e.g., loss of kidney function, uncontrolled infections, multiorgan failure, uncontrolled upper gastrointestinal bleeding, other active malignancies except skin cancer).
  • * Pre-existing mental health conditions that, in the opinion of the investigative team, would interfere with the ability to provide informed consent and understand written and oral instructions (e.g., hepatic encephalopathy, psychotic disorder diagnosis or symptoms).
  • * Current pregnancy.
  • * Be anyone who, based on self-reported withdrawal symptoms and the opinion of the investigative team, could not currently safely be withdrawn from alcohol without medical detoxification.
  • * Currently receiving formalized psychosocial treatment for an alcohol use or drug problem and/or newly taking medications for an alcohol use or drug problem.
  • * Currently receiving formalized behavioral weight management treatment and/or newly taking weight loss medications.

Ages Eligible for Study

21 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Brown University,

Study Record Dates

2025-07