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Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Prediabetic Individuals

Description

The purpose of this study is to investigate the effect of mango intake on metabolic and inflammatory responses relative to meals in individuals at risk of developing diabetes, as well as to understand how the beneficial compounds found in mangoes are absorbed and processed in the body.

Conditions

Pre Diabetes
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Related Conditions:

Pre Diabetes

Study Overview

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Study Details

Study overview

The purpose of this study is to investigate the effect of mango intake on metabolic and inflammatory responses relative to meals in individuals at risk of developing diabetes, as well as to understand how the beneficial compounds found in mangoes are absorbed and processed in the body.

Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Relation to Meal in Prediabetic Individuals

Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Prediabetic Individuals

Condition
Pre Diabetes
Intervention / Treatment

-

Contacts and Locations

Chicago

Clinical Nutrition Research Center, Chicago, Illinois, United States, 60616

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Be between 20-60 years old.
  • * Have a BMI of 25-35 kilograms per square meter.
  • * Have fasting blood glucose between 100-125 milligrams per deciliter or Glycated hemoglobin (HbA1c) between 5.7-6.4%.
  • * Be non-smokers for at least 12 months.
  • * Be generally healthy, with no major organ-related diseases.
  • * Not take medications or supplements that could interfere with the study.
  • * Be able to follow study procedures, including dietary restrictions and scheduled visits.
  • * Smoke, vape, or use marijuana.
  • * Have allergies or intolerance to mangoes or study foods.
  • * Have blood pressure above 160/100 millimeters of Mercury.
  • * Have fasting blood glucose above 125 milligrams per deciliter.
  • * Have a history of major heart disease, stroke, or cancer in the past five years.
  • * Be pregnant, planning to become pregnant, or breastfeeding.
  • * Take anti-inflammatory drugs or certain dietary supplements.
  • * Have had major surgery or trauma in the past two months.
  • * Follow extreme diets (e.g., vegan, Atkins).
  • * Have used antibiotics in the last six weeks.
  • * Have a history of eating disorders or substance abuse in the past two years.
  • * Drink more than three cups of coffee or tea per day.
  • * Have donated blood in the last three months.
  • * Be professional athletes or do excessive exercise.
  • * Have had weight changes of more than 11 pounds in the past two months.
  • * Work overnight shifts.

Ages Eligible for Study

20 Years to 60 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Clinical Nutrition Research Center, Illinois Institute of Technology,

Indika Edirisinghe, PhD., PRINCIPAL_INVESTIGATOR, Illinois Institute of Technology

Britt Burton-Freeman, PhD., PRINCIPAL_INVESTIGATOR, Illinois Institute of Technology

Study Record Dates

2026-12-31