RECRUITING

Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Prediabetic Individuals

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to investigate the effect of mango intake on metabolic and inflammatory responses relative to meals in individuals at risk of developing diabetes, as well as to understand how the beneficial compounds found in mangoes are absorbed and processed in the body.

Official Title

Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Relation to Meal in Prediabetic Individuals

Quick Facts

Study Start:2025-04-14
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06986161

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:20 Years to 60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Be between 20-60 years old.
  2. * Have a BMI of 25-35 kilograms per square meter.
  3. * Have fasting blood glucose between 100-125 milligrams per deciliter or Glycated hemoglobin (HbA1c) between 5.7-6.4%.
  4. * Be non-smokers for at least 12 months.
  5. * Be generally healthy, with no major organ-related diseases.
  6. * Not take medications or supplements that could interfere with the study.
  7. * Be able to follow study procedures, including dietary restrictions and scheduled visits.
  1. * Smoke, vape, or use marijuana.
  2. * Have allergies or intolerance to mangoes or study foods.
  3. * Have blood pressure above 160/100 millimeters of Mercury.
  4. * Have fasting blood glucose above 125 milligrams per deciliter.
  5. * Have a history of major heart disease, stroke, or cancer in the past five years.
  6. * Be pregnant, planning to become pregnant, or breastfeeding.
  7. * Take anti-inflammatory drugs or certain dietary supplements.
  8. * Have had major surgery or trauma in the past two months.
  9. * Follow extreme diets (e.g., vegan, Atkins).
  10. * Have used antibiotics in the last six weeks.
  11. * Have a history of eating disorders or substance abuse in the past two years.
  12. * Drink more than three cups of coffee or tea per day.
  13. * Have donated blood in the last three months.
  14. * Be professional athletes or do excessive exercise.
  15. * Have had weight changes of more than 11 pounds in the past two months.
  16. * Work overnight shifts.

Contacts and Locations

Study Contact

Amandeep K. Sandhu, PhD.
CONTACT
708-563-1576
asandhu2@iit.edu
Chelsea Preiss, M.S.
CONTACT
312-567-5300
cpreiss@iit.edu

Principal Investigator

Indika Edirisinghe, PhD.
PRINCIPAL_INVESTIGATOR
Illinois Institute of Technology
Britt Burton-Freeman, PhD.
PRINCIPAL_INVESTIGATOR
Illinois Institute of Technology

Study Locations (Sites)

Clinical Nutrition Research Center
Chicago, Illinois, 60616
United States

Collaborators and Investigators

Sponsor: Clinical Nutrition Research Center, Illinois Institute of Technology

  • Indika Edirisinghe, PhD., PRINCIPAL_INVESTIGATOR, Illinois Institute of Technology
  • Britt Burton-Freeman, PhD., PRINCIPAL_INVESTIGATOR, Illinois Institute of Technology

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04-14
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2025-04-14
Study Completion Date2026-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Pre Diabetes