RECRUITING

Hair Biomarkers Study

Description

Young children aged 0-4 years may be exposed to adverse childhood experiences (ACEs) and/or early life adversity (ELA), which are linked with worse physical and mental health across their lifespan. On the other hand, positive childhood experiences (PCEs) can build resilience and prevent or protect against these detrimental outcomes. Data analyses will assess the interactions of ACEs, PCEs, parenting, and poverty on the early social psychology of childhood and develop objective measures for altered stress regulation using hair cortisol as a chronic stress biomarker.

Conditions

Healthy
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Related Conditions:

Healthy

Study Overview

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Study Details

Study overview

Young children aged 0-4 years may be exposed to adverse childhood experiences (ACEs) and/or early life adversity (ELA), which are linked with worse physical and mental health across their lifespan. On the other hand, positive childhood experiences (PCEs) can build resilience and prevent or protect against these detrimental outcomes. Data analyses will assess the interactions of ACEs, PCEs, parenting, and poverty on the early social psychology of childhood and develop objective measures for altered stress regulation using hair cortisol as a chronic stress biomarker.

Hair Biomarkers Study

Hair Biomarkers Study

Condition
Healthy
Intervention / Treatment

-

Contacts and Locations

Palo Alto

Stanford University, Palo Alto, California, United States, 94304

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Normal, healthy children aged 6 months to 24 months and their mothers (or father, if mother is not able to participate).
  • 2. Living in Santa Clara County, San Mateo County, or Alameda County in Northern California.
  • 3. Willing to give their home address (in order to receive the study kits at home).
  • 4. Committed to regular follow-up at 6-month intervals for the full study duration of 2 years.
  • 1. Children with tinea capitis, alopecia areata, scalp eczema, dermatitis, or other scalp conditions.
  • 2. Children exposed to systemic steroid therapy for any diagnosis in the 3 months prior to study entry.
  • 3. Children receiving any other prescription drugs that alter HPA axis function or cortisol release, if the period of exposure is 2 weeks or longer within the 3 months prior to study entry.
  • 4. Children with chronic medical conditions such as cystic fibrosis, sickle cell disease, asthma, eczema, or other chronic conditions.
  • 5. Children with known developmental delay, Trisomy-21 and other chromosomal anomalies, seizure disorders, chronic pain, cerebral palsy, or other disabilities.
  • 6. Children whose hair has received chemical exposures (e.g., dying, bleaching, chemical straightening, perming) in the 90 days prior to study entry or for 90 days before each follow-up appointment during the 2-year study period.

Ages Eligible for Study

6 Months to 24 Months

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Stanford University,

Study Record Dates

2029-12