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Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

Description

This study investigates the impact of four standard of care, monitored group exercise regimens (resistance training) on conditioning and hypertrophy in women previously treated for breast cancer. The study will compare two conditioning regimens (6-12-25 and 8x8) and two hypertrophy regimens (5/5/5 cluster sets and double training) to assess changes in VO2 max, muscle mass, and fat mass.

Conditions

CancerBreast Cancer
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Related Conditions:

CancerBreast Cancer

Study Overview

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Study Details

Study overview

This study investigates the impact of four standard of care, monitored group exercise regimens (resistance training) on conditioning and hypertrophy in women previously treated for breast cancer. The study will compare two conditioning regimens (6-12-25 and 8x8) and two hypertrophy regimens (5/5/5 cluster sets and double training) to assess changes in VO2 max, muscle mass, and fat mass.

EXERT-BCHC: Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

Condition
Cancer
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

Allegheny General Hospital, Pittsburgh, Pennsylvania, United States, 15212

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Age 20-89 years
  • 2. Women prescribed exercise as a Standard of Care
  • 3. Women with a biopsy proven diagnosis of ductal carcinoma in situ (DCIS) or invasive carcinoma of the breast
  • 4. Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy.
  • 5. Women undergoing active chemotherapy are not allowed on study. Immunotherapy or targeted agent usage is allowed.
  • 6. Women with \> 6 months of resistance training experience under expert guidance by a CSCS
  • 1. Any current treatment with cytotoxic chemotherapy for breast cancer
  • 2. Inability to safely engage in group sessions of resistance training as deemed by study Pl
  • 3. Severe arthritic, joint, cardiovascular, or musculoskeletal condition deemed by Pl to be unsafe to engage in resistance training
  • 4. Beta blocker or GLP-1 inhibitor medications
  • 5. Pregnant women
  • 6. Males

Ages Eligible for Study

20 Years to 89 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute),

Colin Champ, PRINCIPAL_INVESTIGATOR, AHN Radiation Oncology

Study Record Dates

2026-05-14