RECRUITING

Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study investigates the impact of four standard of care, monitored group exercise regimens (resistance training) on conditioning and hypertrophy in women previously treated for breast cancer. The study will compare two conditioning regimens (6-12-25 and 8x8) and two hypertrophy regimens (5/5/5 cluster sets and double training) to assess changes in VO2 max, muscle mass, and fat mass.

Official Title

EXERT-BCHC: Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

Quick Facts

Study Start:2025-05-21
Study Completion:2026-05-14
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07023887

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:20 Years to 89 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Age 20-89 years
  2. 2. Women prescribed exercise as a Standard of Care
  3. 3. Women with a biopsy proven diagnosis of ductal carcinoma in situ (DCIS) or invasive carcinoma of the breast
  4. 4. Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy.
  5. 5. Women undergoing active chemotherapy are not allowed on study. Immunotherapy or targeted agent usage is allowed.
  6. 6. Women with \> 6 months of resistance training experience under expert guidance by a CSCS
  1. 1. Any current treatment with cytotoxic chemotherapy for breast cancer
  2. 2. Inability to safely engage in group sessions of resistance training as deemed by study Pl
  3. 3. Severe arthritic, joint, cardiovascular, or musculoskeletal condition deemed by Pl to be unsafe to engage in resistance training
  4. 4. Beta blocker or GLP-1 inhibitor medications
  5. 5. Pregnant women
  6. 6. Males

Contacts and Locations

Study Contact

Clinical Trials Contact
CONTACT
412-330-6151
ctgov@ahn.org

Principal Investigator

Colin Champ
PRINCIPAL_INVESTIGATOR
AHN Radiation Oncology

Study Locations (Sites)

Allegheny General Hospital
Pittsburgh, Pennsylvania, 15212
United States

Collaborators and Investigators

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

  • Colin Champ, PRINCIPAL_INVESTIGATOR, AHN Radiation Oncology

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-21
Study Completion Date2026-05-14

Study Record Updates

Study Start Date2025-05-21
Study Completion Date2026-05-14

Terms related to this study

Keywords Provided by Researchers

  • exercise

Additional Relevant MeSH Terms

  • Cancer
  • Breast Cancer