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Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

Description

The aim of this study is to determine the effects of regular cannabidiol (CBD) use on the psychobiological mechanisms of the stress response. This will be achieved by comparing acute stress responses of adults who either use or do not use CBD regularly. Correlates of CBD use, including tobacco use, will be collected.

Conditions

CBDCannabidiolStressAcute Stress Reaction
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Related Conditions:

CBDCannabidiolStressAcute Stress Reaction

Study Overview

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Study Details

Study overview

The aim of this study is to determine the effects of regular cannabidiol (CBD) use on the psychobiological mechanisms of the stress response. This will be achieved by comparing acute stress responses of adults who either use or do not use CBD regularly. Correlates of CBD use, including tobacco use, will be collected.

Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

Condition
CBD
Intervention / Treatment

-

Contacts and Locations

Minneapolis

University of Minnesota, Minneapolis, Minnesota, United States, 55455

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Adults who are relatively healthy and aged 21-70 years.
  • * Must keep a normal sleep schedule (sleep during nighttime, awake during daytime).
  • * Must either (1) use CBD daily/regularly or (2) not use CBD regularly.
  • * Participated in previous acute stress studies that included a similar stress induction.
  • * Current, unstable: major psychiatric disorder or medical condition (e.g., uncontrolled hypertension above 160/100).
  • * Self-reported current pregnancy.
  • * Self-reported current use of illicit substances (other than cannabis).
  • * Non-compliance with instructions for study visit (abstinence from alcohol, caffeine, physical activity, etc.)
  • * Students of the principal researcher

Ages Eligible for Study

21 Years to 70 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Minnesota,

Mustafa al'Absi, PRINCIPAL_INVESTIGATOR, University of Minnesota

Study Record Dates

2026-11-30