RECRUITING

Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The aim of this study is to determine the effects of regular cannabidiol (CBD) use on the psychobiological mechanisms of the stress response. This will be achieved by comparing acute stress responses of adults who either use or do not use CBD regularly. Correlates of CBD use, including tobacco use, will be collected.

Official Title

Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

Quick Facts

Study Start:2025-06-01
Study Completion:2026-11-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07069478

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adults who are relatively healthy and aged 21-70 years.
  2. * Must keep a normal sleep schedule (sleep during nighttime, awake during daytime).
  3. * Must either (1) use CBD daily/regularly or (2) not use CBD regularly.
  1. * Participated in previous acute stress studies that included a similar stress induction.
  2. * Current, unstable: major psychiatric disorder or medical condition (e.g., uncontrolled hypertension above 160/100).
  3. * Self-reported current pregnancy.
  4. * Self-reported current use of illicit substances (other than cannabis).
  5. * Non-compliance with instructions for study visit (abstinence from alcohol, caffeine, physical activity, etc.)
  6. * Students of the principal researcher

Contacts and Locations

Study Contact

Stress and Resilience Research Labs
CONTACT
2187268623
umdbml@d.umn.edu

Principal Investigator

Mustafa al'Absi
PRINCIPAL_INVESTIGATOR
University of Minnesota

Study Locations (Sites)

University of Minnesota
Minneapolis, Minnesota, 55455
United States

Collaborators and Investigators

Sponsor: University of Minnesota

  • Mustafa al'Absi, PRINCIPAL_INVESTIGATOR, University of Minnesota

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06-01
Study Completion Date2026-11-30

Study Record Updates

Study Start Date2025-06-01
Study Completion Date2026-11-30

Terms related to this study

Keywords Provided by Researchers

  • cardiovascular reactivity, , , ,
  • hypothalamic-pituitary-adrenal axis
  • stress
  • mood
  • CBD use

Additional Relevant MeSH Terms

  • CBD
  • Cannabidiol
  • Stress
  • Acute Stress Reaction