RECRUITING

Evaluation of the Genetics of Bipolar Disorder

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Conditions

Bipolar DisorderAffective DisorderDepressionGenetic PolymorphismsMajor DepressionGenome-Wide ScanNatural HistoryPanic Disorder

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study looks to identify genes that may affect a person's chances of developing bipolar disorder (BP) and related conditions....

Official Title

Bipolar Genetics: A Collaborative Study

Quick Facts

Study Start:1994-08-11
Study Completion:N/A
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00001174

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 100 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Stated willingness to comply with all study procedures and availability for the duration of the study.
  2. 2. Male or female, aged 18 years and over. Children are excluded for the following reasons: age at onset of BD is usually later than age 18, the diagnostic and assessment instruments we use are not validated in children.
  3. 3. In good general health as evidenced by medical history or diagnosed with or exhibiting symptoms of bipolar disorder or related conditions not attributable to substance abuse, or neurological disease; OR a 1st or 2nd degree relative of an enrolled participant. Related conditions are defined as those found more often among relatives of people with bipolar disorder or which have been shown to be genetically correlated with bipolar disorder through molecular genetic studies. These include major depression, schizophrenia, panic disorder, and attention deficit hyperactivity disorder.
  4. 4. Ability to safely provide a blood or saliva sample.
  5. 5. Ability of subject to understand and willingness to sign a written informed consent document.
  1. 1. Active alcohol or substance abuse.
  2. 2. Subjects who suffer cognitive impairment and are unable to provide an accurate psychiatric history are excluded since much of the diagnostic information relies on selfreport and recall of past events.

Contacts and Locations

Study Contact

Emily K Besancon
CONTACT
(866) 644-4363
emily.besancon@nih.gov
Francis J McMahon, M.D.
CONTACT
(301) 451-4455
mcmahonf@mail.nih.gov

Principal Investigator

Francis J McMahon, M.D.
PRINCIPAL_INVESTIGATOR
National Institute of Mental Health (NIMH)

Study Locations (Sites)

National Institutes of Health Clinical Center
Bethesda, Maryland, 20892
United States

Collaborators and Investigators

Sponsor: National Institute of Mental Health (NIMH)

  • Francis J McMahon, M.D., PRINCIPAL_INVESTIGATOR, National Institute of Mental Health (NIMH)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date1994-08-11
Study Completion DateN/A

Study Record Updates

Study Start Date1994-08-11
Study Completion DateN/A

Terms related to this study

Keywords Provided by Researchers

  • Affective Disorder
  • Depression
  • Genetic Polymorphisms
  • Major Depression
  • Genome-Wide Scan
  • Natural History
  • Panic Disorder
  • Bipolar Disorder

Additional Relevant MeSH Terms

  • Bipolar Disorder