RECRUITING

Studies of Blood Flow to the Brain During Thought

Conditions

Healthy Volunteer Cognition Vision Cortex Visual Processing Magnetic Resonance Imaging Natural History

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to use brain imaging technology to measure changes in blood flow to areas in the brain as individuals perform intellectual tasks. This study will use functional magnetic resonance imaging (fMRI) to examine blood flow to areas of the brain as participants engage in tasks associated with visual perception, visual recognition, and memory....

Official Title

Regional Cerebral Blood Flow Studies of Object Perception, Identification, Localization, and Memory

Quick Facts

Study Start:1993-09-17

Study Completion:N/A

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT00001360

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Healthy adults, with at least a high school education, aged 18 to 65 years, will be recruited to participate in the study. * Able to read and write in English to guarantee understanding of all written and spoken instructions, which are in English.	* have evidence of, or a history of: * major medical, neurological or psychiatric illness * serious head injury * learning disability-drug or alcohol abuse or dependence in the past 3 months, except nicotine * Female subjects who are pregnant or have a positive pregnancy test 24 hours prior to an experiment will be excluded from neuroimaging studies. * All subjects will be questioned prior to MRI scanning for possible occupational exposure to metal slivers or shavings, which may have become accidentally lodged in the tissues of the head or neck. Subjects with surgical clips or shrapnel in or near the brain or blood vessels, subjects with cochlear implants, subjects with any metallic body in the eye or CNS, and subjects with any form of implant wire or metal device which may concentrate radiofrequency fields will be excluded from MRI scanning experiments because of possible risks during MRI scanning. Those whose history is suggestive of such a problem will also be excluded from the MRI portion of the experiments. They may still participate in the behavioral and MEG experiments. * Subjects unable to lie flat on their back for up to 3 hours may not be eligible to participate in MRI scans.

Inclusion Criteria

Exclusion Criteria

* Healthy adults, with at least a high school education, aged 18 to 65 years, will be recruited to participate in the study.
* Able to read and write in English to guarantee understanding of all written and spoken instructions, which are in English.

* have evidence of, or a history of:
* major medical, neurological or psychiatric illness
* serious head injury
* learning disability-drug or alcohol abuse or dependence in the past 3 months, except nicotine
* Female subjects who are pregnant or have a positive pregnancy test 24 hours prior to an experiment will be excluded from neuroimaging studies.
* All subjects will be questioned prior to MRI scanning for possible occupational exposure to metal slivers or shavings, which may have become accidentally lodged in the tissues of the head or neck. Subjects with surgical clips or shrapnel in or near the brain or blood vessels, subjects with cochlear implants, subjects with any metallic body in the eye or CNS, and subjects with any form of implant wire or metal device which may concentrate radiofrequency fields will be excluded from MRI scanning experiments because of possible risks during MRI scanning. Those whose history is suggestive of such a problem will also be excluded from the MRI portion of the experiments. They may still participate in the behavioral and MEG experiments.
* Subjects unable to lie flat on their back for up to 3 hours may not be eligible to participate in MRI scans.

Contacts and Locations

Study Contact

NIMH LBC Volunteer

CONTACT

(301) 827-5157

nimhlbcvolunteer@mail.nih.gov

Christopher I Baker, Ph.D.

CONTACT

(301) 435-6058

bakerchris@mail.nih.gov

Principal Investigator

Christopher I Baker, Ph.D.

PRINCIPAL_INVESTIGATOR

National Institute of Mental Health (NIMH)

Study Locations (Sites)

National Institutes of Health Clinical Center

Bethesda, Maryland, 20892

United States

Collaborators and Investigators

Sponsor: National Institute of Mental Health (NIMH)

Christopher I Baker, Ph.D., PRINCIPAL_INVESTIGATOR, National Institute of Mental Health (NIMH)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date1993-09-17

Study Completion DateN/A

Study Record Updates

Study Start Date1993-09-17

Study Completion DateN/A

Terms related to this study

Keywords Provided by Researchers

Cognition
Vision
Cortex
Visual Processing
Magnetic Resonance Imaging
Natural History

Additional Relevant MeSH Terms

Healthy Volunteer