A Prospective Database of Infants With Cholestasis

Description

Biliary atresia, idiopathic neonatal hepatitis, and specific genetic cholestatic conditions are the most common causes of jaundice and hyperbilirubinemia that continue beyond the newborn period. The long term goal of the Childhood Liver Disease Research Network (ChiLDReN) is to establish a database of clinical information and plasma, serum, and tissue samples from cholestatic children to facilitate research and to perform clinical, epidemiological and therapeutic trials in these important pediatric liver diseases.

Conditions

Biliary Atresia, Neonatal Cholestasis

Study Overview

Study Details

Study overview

Biliary atresia, idiopathic neonatal hepatitis, and specific genetic cholestatic conditions are the most common causes of jaundice and hyperbilirubinemia that continue beyond the newborn period. The long term goal of the Childhood Liver Disease Research Network (ChiLDReN) is to establish a database of clinical information and plasma, serum, and tissue samples from cholestatic children to facilitate research and to perform clinical, epidemiological and therapeutic trials in these important pediatric liver diseases.

Childhood Liver Disease Research Network (ChiLDReN): A Prospective Database of Infants With Cholestasis

A Prospective Database of Infants With Cholestasis

Condition
Biliary Atresia
Intervention / Treatment

-

Contacts and Locations

Los Angeles

Children's Hospital Los Angeles, Los Angeles, California, United States, 90027

San Francisco

University of California, San Francisco, California, United States, 94143

Aurora

Children's Hospital Colorado, Aurora, Colorado, United States, 80045

Atlanta

Children's Healthcare of Atlanta - Emory University, Atlanta, Georgia, United States, 30322

Chicago

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States, 60614

Indianapolis

Riley Hospital for Children, Indianapolis, Indiana, United States, 46202

Baltimore

Johns Hopkins School of Medicine, Baltimore, Maryland, United States, 21287

Saint Louis

Washington University School of Medicine, Saint Louis, Missouri, United States, 63110

New York

Mount Sinai Medical Center, New York, New York, United States, 10029

Cincinnati

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States, 45229

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    to 6 Months

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    Arbor Research Collaborative for Health,

    Saul Karpen, MD, PhD, STUDY_CHAIR, Children's Healthcare of Atlanta - Emory University

    Ed Doo, MD, STUDY_DIRECTOR, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    John Magee, MD, PRINCIPAL_INVESTIGATOR, University of Michigan Medical Center, Ann Arbor

    Lisa Henn, PhD, PRINCIPAL_INVESTIGATOR, Arbor Research Collaborative of Health

    Averell Sherker, MD, STUDY_DIRECTOR, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    Study Record Dates

    2029-05