Intrinsic Optical Imaging Study to Map Neocortical Seizure in Human Epilepsy Patients

Description

The purpose of this study is to develop a technique for the intraoperative identification of human functional and epileptiform cortex using intrinsic signal imaging. The investigators propose that the ability to optically monitor neuronal activity in a large area of cortex in "real-time" will be a more sensitive and time-saving method than the electrical methods currently available. The applications of this technique will not only theoretically increase the safety and efficacy of many of neurosurgical procedures, but will be useful as an investigational tool to study human cortical physiology.

Conditions

Epilepsy

Study Overview

Study Details

Study overview

The purpose of this study is to develop a technique for the intraoperative identification of human functional and epileptiform cortex using intrinsic signal imaging. The investigators propose that the ability to optically monitor neuronal activity in a large area of cortex in "real-time" will be a more sensitive and time-saving method than the electrical methods currently available. The applications of this technique will not only theoretically increase the safety and efficacy of many of neurosurgical procedures, but will be useful as an investigational tool to study human cortical physiology.

Intraoperative Optical Mapping of Human Epileptiform and Functional Cortex

Intrinsic Optical Imaging Study to Map Neocortical Seizure in Human Epilepsy Patients

Condition
Epilepsy
Intervention / Treatment

-

Contacts and Locations

New York

Weill Cornell Medical College/New York Presbyterian Hospital, New York, New York, United States, 10021

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Medically intractable epilepsy
  • * Subjects undergoing neurosurgical operations requiring cortical mapping
  • * Subjects NOT undergoing neurosurgical operations requiring cortical mapping.

Ages Eligible for Study

6 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Weill Medical College of Cornell University,

Theodore H Schwartz, MD, PRINCIPAL_INVESTIGATOR, Weill Cornell Medical College/New York Presbyterian Hospital

Study Record Dates

2025-12