RECRUITING

Brain Development Research Program

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Dr. Elliott Sherr and his collaborators at University of California, San Francisco (UCSF) are studying the genetic causes of disorders of cognition and epilepsy, in particular disorders of brain development that affect the corpus callosum, such as Aicardi syndrome, as well as two additional brain malformations, polymicrogyria and Dandy-Walker malformation. The goal of the investigators' research is to use a better understanding of the underlying genetic causes as a foundation to develop better treatments for these groups of patients.

Official Title

Disorders of Cerebral Development: A Phenotypic and Genetic Analysis

Quick Facts

Study Start:2003-08
Study Completion:2025-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00305305

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Clinical diagnosis of agenesis or dysgenesis of the corpus callosum, polymicrogyria, or Dandy-Walker malformation
  2. * Should be confirmed by an MRI (Magnetic Resonance Imaging) of the brain
  1. * Fully formed but hypoplastic corpus callosum

Contacts and Locations

Study Contact

Carolyn Le, BA, BS
CONTACT
415-502-8039
Carolyn.Le@ucsf.edu

Principal Investigator

Elliott H Sherr, MD, PhD
PRINCIPAL_INVESTIGATOR
University of California, San Francisco
James Barkovich, MD
PRINCIPAL_INVESTIGATOR
University of California, San Francisco
Pratik Mukherjee, MD, PhD
PRINCIPAL_INVESTIGATOR
University of California, San Francisco

Study Locations (Sites)

University of California, San francisco
San Francisco, California, 94143
United States

Collaborators and Investigators

Sponsor: University of California, San Francisco

  • Elliott H Sherr, MD, PhD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco
  • James Barkovich, MD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco
  • Pratik Mukherjee, MD, PhD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2003-08
Study Completion Date2025-01

Study Record Updates

Study Start Date2003-08
Study Completion Date2025-01

Terms related to this study

Keywords Provided by Researchers

  • Agenesis Corpus Callosum
  • Polymicrogyria
  • Dandy-Walker
  • Brain Malformation
  • Autism
  • Epilepsy
  • Mental Retardation
  • MRI
  • Agenesis of the Corpus Callosum (complete or partial)
  • Confirmed by a brain MRI.
  • Aicardi Syndrome.

Additional Relevant MeSH Terms

  • Brain Disorders
  • Aicardi Syndrome