RECRUITING

Effects of Oncological Treatment During Pregnancy on Mother and Child

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The researchers aim to investigate the outcome (overall survival) of mothers who are diagnosed and/or treated for cancer during pregnancy. Furthermore they want to test the hypothesis that children who were exposed to cancer or cancer treatment (cytotoxic drugs, radiation therapy, targeted therapy,...) develop normally (neurologic and cardiologic examination).

Official Title

Oncological Treatment During Pregnancy: Pharmacokinetics of Chemotherapy and Long Term Follow up of the Offspring

Quick Facts

Study Start:2005-08
Study Completion:2032-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00330447

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Histologically proven cancer in association with a pregnancy (during pregnancy or cancer dagnosis within 5 years after pregnancy)
  2. * \> 18 years of age, premenopausal
  3. * Patients who have given their signed and written informed consent to participate in the trial after fully understanding the implication of the protocol
  4. * Women receiving any cytotoxic drug or radiation therapy during pregnancy are allowed for the assessment of the maternal and fetal outcome (Part II).
  1. * Mentally disabled or significantly altered mental status that would prohibit the understanding and giving of informed consent

Contacts and Locations

Study Contact

Ayaka Wakatsuki
CONTACT
+32 16 34 41 69
ayaka.wakatsuki@uzleuven.be
Kristel Van Calsteren, MD PhD
CONTACT
+32-16-346192
kristel.vancalsteren@uzleuven.be

Principal Investigator

Amant Frederic, MD PhD
PRINCIPAL_INVESTIGATOR
KULeuven, Belgium

Study Locations (Sites)

Cooper University Hospital (2015-ongoing)
Camden, New Jersey, 08103
United States

Collaborators and Investigators

Sponsor: University Hospital, Gasthuisberg

  • Amant Frederic, MD PhD, PRINCIPAL_INVESTIGATOR, KULeuven, Belgium

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2005-08
Study Completion Date2032-12

Study Record Updates

Study Start Date2005-08
Study Completion Date2032-12

Terms related to this study

Keywords Provided by Researchers

  • pregnancy
  • in utero
  • chemotherapy
  • radiotherapy
  • cancer
  • offspring
  • neonatal
  • long term
  • follow up
  • cancer during pregnancy
  • chemotherapy and radiotherapy during pregnancy
  • long term follow up of children

Additional Relevant MeSH Terms

  • Cancer
  • Pregnancy