RECRUITING

Identifying Genetic Causes of IC/BPS

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Interstitial cystitis (IC), also called Bladder Pain syndrome (BPS) is a common condition with no known cause or cure. Twin studies and family accounts have suggested that the condition may be genetic or passed down (inherited) from one generation to another. In this study, the investigators are collecting genetic material via blood or saliva and medical information from families in North America in an attempt to identify genetic factors that may cause IC/BPS. The investigators are enrolling inviduals with IC/BPS and their family members (family members with and without IC like symptoms). Travel to Boston not required.

Official Title

Genetic Studies in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)

Quick Facts

Study Start:2006-01-15
Study Completion:2030-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00389142

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:1 Year
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Diagnosis of IC/BPS
  2. * Males and females of any age
  3. * Urinary frequency - more than 1X/hour, and/or
  4. * Dysuria, and/or
  5. * Pelvic, suprapubic, or abdominal pain - for 3 months or longer
  6. * Nocturia
  7. * Normal urinary stream (by history)
  8. * No evidence of active bacterial UTI (no pyuria \& negative urinary culture for last 3 months)
  9. * First degree relative of someone with above symptoms
  1. * Major structural/anatomical urinary tract abnormalities by ultrasound
  2. * Underlying inborn conditions affecting the urinary tract
  3. * Surgery/chemotherapy affected pelvic area
  4. * GI or GU cancers
  5. * Severe Constipation in children only

Contacts and Locations

Study Contact

Elicia A Estrella, MS, LCGC
CONTACT
617-919-4552
elicia.estrella@childrens.harvard.edu
Stephanie Brewster, MS, LCGC
CONTACT
Stephanie.Brewster@childrens.harvard.edu

Principal Investigator

Catherine Brownstein, Ph.D.
PRINCIPAL_INVESTIGATOR
Boston Children's Hosptial

Study Locations (Sites)

Boston Children's Hospital (BCH)
Boston, Massachusetts, 02115
United States

Collaborators and Investigators

Sponsor: Boston Children's Hospital

  • Catherine Brownstein, Ph.D., PRINCIPAL_INVESTIGATOR, Boston Children's Hosptial

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2006-01-15
Study Completion Date2030-12-31

Study Record Updates

Study Start Date2006-01-15
Study Completion Date2030-12-31

Terms related to this study

Keywords Provided by Researchers

  • pelvic pain
  • urinary frequency
  • painful bladder
  • urinary urgency

Additional Relevant MeSH Terms

  • Interstitial Cystitis
  • Bladder Pain Syndrome