RECRUITING

Intraocular Lens Power Calculation After Laser Refractive Surgery Based on Optical Coherence Tomography

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The long-term goal of this project is to utilize very high-speed optical coherence tomography (OCT) technology to guide surgical treatments of corneal diseases. OCT is well known for its exquisite resolution, but until recently it has not had sufficient speed to capture the shape of the cornea because of eye motion during OCT scanning. The development of Fourier-domain (FD) OCT technology has made the requisite speed possible. The objective of this project is to develop methods for imaging the cornea with an FD-OCT system that will precisely measure corneal shape and use this information to guide surgery. Cataract surgery in patients with previous laser vision correction often leads to significant near- or far-sightedness, a problem that could be resolved by using a more accurate intraocular lens power selection formula based on the measurement of corneal refractive power with OCT.

Official Title

Guiding the Treatment of Anterior Eye Diseases With Optical Coherence Tomography

Quick Facts

Study Start:2011-04
Study Completion:2026-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00532051

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * The subjects will be patients seeking cataract surgery with implantation of monofocal IOLs (including toric IOLs) but not multifocal or accommodative IOLs.
  2. * Subjects will have had post-laser vision correction (LVC) such as previous LASIK, PRK, laser sub-epithelial keratectomy (LASEK), epi-LASIK (surface laser ablation under a microkeratome-created epithelial flap) or RK. The post-LVC group will be subdivided into those who have previous hyperopic LVC and those who have previous myopic LVC.
  1. * Inability to give informed consent.
  2. * Inability to maintain stable fixation for OCT imaging.
  3. * Inability to commit to required visits to complete the study.
  4. * Eyes with concurrent cataract, retinal diseases, glaucoma, or other eye conditions that may limit the visual outcome after surgery.

Contacts and Locations

Study Contact

Humberto Martinez, COT
CONTACT
503-494-7712
martinhu@ohsu.edu
Denny Romfh, OD
CONTACT
503-494-4351
romfhd@ohsu.edu

Principal Investigator

David Huang, MD, PhD
PRINCIPAL_INVESTIGATOR
Casey Eye Institute, Oregon Health & Science University

Study Locations (Sites)

Casey Eye Institute, Oregon Health & Science University
Portland, Oregon, 97239
United States

Collaborators and Investigators

Sponsor: Oregon Health and Science University

  • David Huang, MD, PhD, PRINCIPAL_INVESTIGATOR, Casey Eye Institute, Oregon Health & Science University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2011-04
Study Completion Date2026-07

Study Record Updates

Study Start Date2011-04
Study Completion Date2026-07

Terms related to this study

Keywords Provided by Researchers

  • cataract, lasik, laser refractive surgery

Additional Relevant MeSH Terms

  • Cataract