The Hydrocephalus Clinical Research Network (HCRN) has been established by philanthropic funding to conduct multi-institutional research (clinical trials and observational studies) on pediatric hydrocephalus. In addition to philanthropic funding, the HCRN has also received an NIH NINDS Challenge Grant to support the network infrastructure which allows for the conduct of this and other network studies. The HCRN consists of multiple Clinical Centers and the Data Coordinating Center (DCC). The HCRN Core Data Project will obtain data about all neurosurgical hydrocephalus events from the network Clinical Centers, and create a database to be used by HCRN investigators. The ongoing maintenance of the Core Data Project serves two main purposes: 1) it will help investigators understand the variability, progression, and current treatment practices for hydrocephalus in children, with an ultimate goal of better guiding and assessing therapeutic intervention and providing recommendations on patient care and, 2) it will provide pilot and descriptive data necessary for hypothesis generation and study design (i.e. preliminary power analyses, recruitment projections) for studies under development by the HCRN. This multi-institutional database will be maintained throughout the lifetime of the HCRN, and may be useful for tracking trends in pediatric hydrocephalus over time. The Core Data Project will be an invaluable resource to the HCRN and will help stimulate new research protocols, identify potential need for future expansion of the network to incorporate additional patient populations, and provide a descriptive understanding of children with hydrocephalus cared for within the network.
Pediatric Hydrocephalus
The Hydrocephalus Clinical Research Network (HCRN) has been established by philanthropic funding to conduct multi-institutional research (clinical trials and observational studies) on pediatric hydrocephalus. In addition to philanthropic funding, the HCRN has also received an NIH NINDS Challenge Grant to support the network infrastructure which allows for the conduct of this and other network studies. The HCRN consists of multiple Clinical Centers and the Data Coordinating Center (DCC). The HCRN Core Data Project will obtain data about all neurosurgical hydrocephalus events from the network Clinical Centers, and create a database to be used by HCRN investigators. The ongoing maintenance of the Core Data Project serves two main purposes: 1) it will help investigators understand the variability, progression, and current treatment practices for hydrocephalus in children, with an ultimate goal of better guiding and assessing therapeutic intervention and providing recommendations on patient care and, 2) it will provide pilot and descriptive data necessary for hypothesis generation and study design (i.e. preliminary power analyses, recruitment projections) for studies under development by the HCRN. This multi-institutional database will be maintained throughout the lifetime of the HCRN, and may be useful for tracking trends in pediatric hydrocephalus over time. The Core Data Project will be an invaluable resource to the HCRN and will help stimulate new research protocols, identify potential need for future expansion of the network to incorporate additional patient populations, and provide a descriptive understanding of children with hydrocephalus cared for within the network.
HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN)
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Children's Hospital of Alabama, University of Alabama, Birmingham, Alabama, United States, 35233
Children's Hospital of Los Angeles, Los Angeles, California, United States, 90027
Children's Hospital Colorado, Aurora, Colorado, United States, 80045
Johns Hopkins Children's Center, Baltimore, Maryland, United States, 21287
St. Louis Children's Hospital, St. Louis, Missouri, United States, 63110
Nationwide Children's Hospital, Columbus, Ohio, United States, 43205
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States, 15224
Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee, United States, 37232
Texas Children's Hospital, Houston, Texas, United States, 77030
Primary Children's Hospital, Salt Lake City, Utah, United States, 84118
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
to 18 Years
ALL
No
University of Utah,
Jay Riva-Cambrin, MD, STUDY_CHAIR, Alberta Children's Hospital
Abhaya Kulkarni, MD, PhD, PRINCIPAL_INVESTIGATOR, Sick Children's Hospital, Toronto, Ontario
Tamara D Simon, MD, MSPH, PRINCIPAL_INVESTIGATOR, University of Washington / Seattle Children's Hospital
Richard Holubkov, Ph.D., PRINCIPAL_INVESTIGATOR, University of Utah
2029-12