Pharmacogenetic Determinants Of Treatment Response In Children

Description

To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the disposition or effects of these xenobiotic substrates. To investigate the nature of heritability and the genetic basis of pharmacogenetic traits by studying family members of individuals with specific genotypes.

Conditions

All Malignancies, Children Being Treated for Catastrophic Illness

Study Overview

Study Details

Study overview

To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the disposition or effects of these xenobiotic substrates. To investigate the nature of heritability and the genetic basis of pharmacogenetic traits by studying family members of individuals with specific genotypes.

Pharmacogenetic Determinants Of Treatment Response In Children

Pharmacogenetic Determinants Of Treatment Response In Children

Condition
All Malignancies
Intervention / Treatment

-

Contacts and Locations

Memphis

St. Jude Children's Research Hospital, Memphis, Tennessee, United States, 38105

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Any patients under evaluation/treatment at St. Jude Children's Research Hospital (SJCRH)
  • * Parents or family members of St. Jude patients
  • * Non patient volunteers
  • * All study subjects must provide informed consent for participation
  • * Assent/Consent of the patient (parent) must be provided prior to attempts made by investigators to enroll a family member of a SJCRH patient

Ages Eligible for Study

to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

St. Jude Children's Research Hospital,

Clinton F. Stewart, Pharm.D., PRINCIPAL_INVESTIGATOR, St. Jude Children's Research Hospital

Study Record Dates

2034-03