RECRUITING

Establishment of a Lifetime of Cohort of Adults Surviving Childhood Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Childhood cancer predisposes to health risks that may not become apparent until many years after completion of therapy. The SJLIFE protocol is designed to establish a lifetime cohort of childhood cancer survivors treated at St. Jude Children's Research Hospital to facilitate evaluation of health outcomes in aging adults surviving pediatric cancer. The study focuses on the following Primary and secondary objectives: * To establish a lifetime cohort of childhood cancer survivors treated at St. Jude Children's Research Hospital to facilitate evaluation of health outcomes in aging children and adults surviving pediatric cancer. * To estimate the prevalence, cumulative incidence, and latency of selected late treatment complications following predisposing therapeutic exposures in children and adults surviving pediatric cancer. * To identify treatment, genetic, demographic, and psychosocial / behavioral related predictors of adverse health outcomes. * To develop risk profiles for adverse health outcomes across the age spectrum to guide development of clinical screening guidelines and risk-reducing interventions. * To identify factors that may be protective against the development of specific late treatment complications. * To generate data for a series of future hypothesis-driven trials * To serve as a source for the collection of samples from child and adult volunteers for future SJLIFE research. * To collect health outcomes data on a community control population for comparison purposes.

Official Title

Establishment of a Lifetime of Cohort of Adults Surviving Childhood Cancer

Quick Facts

Study Start:2007-09-13
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00760656

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:5 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patient will have a diagnosis of childhood malignancy (or neoplasm requiring similar therapy) that was treated or followed at St. Jude Children's Research Hospital.
  2. * Patient will be at least five years from diagnosis.
  3. * Patient is willing to participate at any level of study
  4. * Patient is willing to comply with the guidelines of St. Jude domiciliary care facilities
  5. * Patient or legally authorized representative must sign informed consent for study participation.
  6. * ≥5 years of age
  7. * Non-first degree relatives or friends of St. Jude patients or former patients or SJCRH employees/affiliates who are not SJLIFE study team members, or family members of SJLIFE study team, or supervised by a SJLIFE study team members, or any volunteer not associated with St. Jude.
  8. * Participant does not have a diagnosis of childhood malignancy or childhood neoplasm requiring similar therapy (i.e., diagnosed \<21 years of age).
  9. * Participant is not currently pregnant or lactating.
  10. * Patient is willing to comply with the guidelines of St. Jude domiciliary care facilities.
  11. * Patient must sign informed consent for study participation.
  1. * Patient or control subject refuses to participate at any level of study

Contacts and Locations

Study Contact

Melissa Hudson, MD
CONTACT
1-866-278-5833
referralinfo@stjude.org

Principal Investigator

Melissa Hudson, MD
PRINCIPAL_INVESTIGATOR
St. Jude Children's Research Hospital

Study Locations (Sites)

St. Jude Children's Research Hospital
Memphis, Tennessee, 38105
United States

Collaborators and Investigators

Sponsor: St. Jude Children's Research Hospital

  • Melissa Hudson, MD, PRINCIPAL_INVESTIGATOR, St. Jude Children's Research Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2007-09-13
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2007-09-13
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • Health outcomes in adults who survived pediatric cancer
  • Survivors of Pediatric Cancer

Additional Relevant MeSH Terms

  • Cancer