Mechanisms Underlying Impaired Diabetic Wound Healing

Description

The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.

Conditions

Non-healing Wounds, Diabetes

Study Overview

Study Details

Study overview

The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.

Mechanisms Underlying Impaired Diabetic Wound Healing

Mechanisms Underlying Impaired Diabetic Wound Healing

Condition
Non-healing Wounds
Intervention / Treatment

-

Contacts and Locations

Indianapolis

Comprehensive Wound Care Centers, Indianapolis, Indiana, United States, 46202

Columbus

Comprehensive Wound Care Centers, Columbus, Ohio, United States, 43210

Pittsburgh

University of Pittsburgh - McKeesport, Pittsburgh, Pennsylvania, United States, 15132

Pittsburgh

University of Pittsburgh - Mercy, Pittsburgh, Pennsylvania, United States, 15219

Pittsburgh

University of Pittsburgh - Passavant, Pittsburgh, Pennsylvania, United States, 16066

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Ages 21-80
  • * Chronic Wound (present \>4 weeks)
  • * Diabetic \& Non-diabetic
  • * Adult surgical wounds
  • * Inability to consent
  • * Pregnant women
  • * Therapeutically immunocompromised
  • * Individuals defined in 45 CFR 46 Subparts B,C, and D, nor from any other population considered vulnerable 2.9

Ages Eligible for Study

21 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pittsburgh,

Sashwati Roy, Ph.D., PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

2030-12-31