RECRUITING

Mechanisms Underlying Impaired Diabetic Wound Healing

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.

Official Title

Mechanisms Underlying Impaired Diabetic Wound Healing

Quick Facts

Study Start:2008-09-01
Study Completion:2030-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00777712

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Ages 21-80
  2. * Chronic Wound (present \>4 weeks)
  3. * Diabetic \& Non-diabetic
  4. * Adult surgical wounds
  1. * Inability to consent
  2. * Pregnant women
  3. * Therapeutically immunocompromised
  4. * Individuals defined in 45 CFR 46 Subparts B,C, and D, nor from any other population considered vulnerable 2.9

Contacts and Locations

Study Contact

Josephine Vidic, BS
CONTACT
4126240422
jbv9@pitt.edu
Piya Das Ghatak, PhD
CONTACT
4126240422
piya.dasghatak@pitt.edu

Principal Investigator

Sashwati Roy, Ph.D.
PRINCIPAL_INVESTIGATOR
University of Pittsburgh

Study Locations (Sites)

Comprehensive Wound Care Centers
Indianapolis, Indiana, 46202
United States
Comprehensive Wound Care Centers
Columbus, Ohio, 43210
United States
University of Pittsburgh - McKeesport
Pittsburgh, Pennsylvania, 15132
United States
University of Pittsburgh - Mercy
Pittsburgh, Pennsylvania, 15219
United States
University of Pittsburgh - Passavant
Pittsburgh, Pennsylvania, 16066
United States

Collaborators and Investigators

Sponsor: University of Pittsburgh

  • Sashwati Roy, Ph.D., PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2008-09-01
Study Completion Date2030-12-31

Study Record Updates

Study Start Date2008-09-01
Study Completion Date2030-12-31

Terms related to this study

Keywords Provided by Researchers

  • Wound healing
  • diabetes
  • inflammatory cell
  • monocyte
  • leukocyte
  • macrophage

Additional Relevant MeSH Terms

  • Non-healing Wounds
  • Diabetes