RECRUITING

Evaluation of Patients With Non-obstructive Coronary Arteries

Conditions

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Patients with angina and non-obstructive CAD are common within clinical practice, but remain a challenge with regard to diagnosis and treatment. When these patients undergo a comprehensive evaluation at the time of invasive coronary angiography, occult coronary abnormalities are frequently found. We hope to learn the overall prevalence and presentation of these occult coronary abnormalities and its long term outcome in this patient population.

Official Title

Evaluation of Patients With Angina in the Absence of Obstructive Coronary Artery Disease

Quick Facts

Study Start:2007-06

Study Completion:2047-06

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT00823563

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
1. Patient referred for elective coronary angiography because of a reasonable clinical suspicion of coronary ischemia. 2. Presence of angina or an anginal equivalent (including chest, back, shoulder, arm, neck, jaw discomfort, or shortness of breath brought on by physical exertion, emotional stress, or certain times of day/month).	1. Asymptomatic (such as a pre-op cath) 2. Status-post heart transplant 3. Age \<18 4. Renal insufficiency (creatinine \>1.5) 5. Presence of an acute coronary syndrome (STEMI or NSTEMI), Tako-tsubo, an abnormal ejection fraction (EF\<55%), cardiogenic shock, or recent VT/VF 6. Presence of another likely explanation of chest pain, such as pulmonary hypertension or aortic stenosis 7. History of adverse reaction to any of the medications being used (acetylcholine, nitroglycerin, adenosine, or heparin) 8. Currently taking vasoactive medication (such as nitroglycerin) 9. Inability to provide an informed consent, including an inability to speak, read, or understand English, Spanish, Chinese, Farsi, Japanese, Korean, Russian, or Vietnamese 10. A hearing impairment that won't allow for a typical verbal conversation or a visual impairment that won't allow for reading of the written consent 11. Participation in another study (with the exception of the Stanford Gene-PAD study) 12. A potentially vulnerable subject (including minors, pregnant women, economically and educationally disadvantaged, decisionally impaired, and homeless people)

Inclusion Criteria

Exclusion Criteria

1. Patient referred for elective coronary angiography because of a reasonable clinical suspicion of coronary ischemia.
2. Presence of angina or an anginal equivalent (including chest, back, shoulder, arm, neck, jaw discomfort, or shortness of breath brought on by physical exertion, emotional stress, or certain times of day/month).

1. Asymptomatic (such as a pre-op cath)
2. Status-post heart transplant
3. Age \<18
4. Renal insufficiency (creatinine \>1.5)
5. Presence of an acute coronary syndrome (STEMI or NSTEMI), Tako-tsubo, an abnormal ejection fraction (EF\<55%), cardiogenic shock, or recent VT/VF
6. Presence of another likely explanation of chest pain, such as pulmonary hypertension or aortic stenosis
7. History of adverse reaction to any of the medications being used (acetylcholine, nitroglycerin, adenosine, or heparin)
8. Currently taking vasoactive medication (such as nitroglycerin)
9. Inability to provide an informed consent, including an inability to speak, read, or understand English, Spanish, Chinese, Farsi, Japanese, Korean, Russian, or Vietnamese
10. A hearing impairment that won't allow for a typical verbal conversation or a visual impairment that won't allow for reading of the written consent
11. Participation in another study (with the exception of the Stanford Gene-PAD study)
12. A potentially vulnerable subject (including minors, pregnant women, economically and educationally disadvantaged, decisionally impaired, and homeless people)

Contacts and Locations

Study Contact

Vedant Pargaonkar, MD

CONTACT

(650) 498-1195

vedantsp@stanford.edu

Principal Investigator

Jennifer A Tremmel, MD, MS

PRINCIPAL_INVESTIGATOR

Stanford University

Study Locations (Sites)

Stanford University School of Medicine

Stanford, California, 94305

United States

Collaborators and Investigators

Sponsor: Stanford University

Jennifer A Tremmel, MD, MS, PRINCIPAL_INVESTIGATOR, Stanford University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2007-06

Study Completion Date2047-06

Study Record Updates

Study Start Date2007-06

Study Completion Date2047-06

Terms related to this study

Additional Relevant MeSH Terms

Chest Pain
Ischemia