RECRUITING

Type 1 Diabetes Recurrence in Pancreas Transplants

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The hypothesis is that humoral and cellular islet-specific responses are an early risk factor for recurrence of autoimmunity and hyperglycemia in simultaneous pancreas-kidney (SPK) recipients independent of alloimmunity. This study will test the hypothesis and will assess their individual and combined predictive value.

Official Title

Recurrence of T1D in Pancreas Transplantation

Quick Facts

Study Start:2005-05
Study Completion:2025-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT01047865

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patient has been fully informed and has signed a dated IRB approval informed consent form and is willing to follow study procedures for the extent of the study (24 months). Parent or legal guardian must provide written consent for patients \<18 years of age.
  2. * Age 18-75 years.
  3. * Recipient of simultaneous pancreas and kidney transplant
  4. * Primary or secondary renal allograft: living or deceased
  1. * Patient has previously received or is receiving an organ transplant other than a pancreas-kidney.

Contacts and Locations

Study Contact

George Burke, M.D.
CONTACT
305-355-5111
gburke@med.miami.edu
Lissett Moni
CONTACT
3053555728
ltueros@med.miami.edu

Principal Investigator

George Burke, M.D.
PRINCIPAL_INVESTIGATOR
University of Miami

Study Locations (Sites)

University of Miami Miller School of Medicine Transplant Clinic
Miami, Florida, 33136
United States

Collaborators and Investigators

Sponsor: University of Miami

  • George Burke, M.D., PRINCIPAL_INVESTIGATOR, University of Miami

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2005-05
Study Completion Date2025-05

Study Record Updates

Study Start Date2005-05
Study Completion Date2025-05

Terms related to this study

Keywords Provided by Researchers

  • Type 1 Diabetes (T1D)
  • Autoimmunity

Additional Relevant MeSH Terms

  • Diabetes Mellitus, Type 1