RECRUITING

Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to prospectively collect specimens from pediatric patients with diffuse intrinsic pontine glioma or brainstem glioma, either during therapy or at autopsy, in order to characterize the molecular abnormalities of this tumor.

Official Title

Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

Quick Facts

Study Start:2010-04
Study Completion:2030-04
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT01106794

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 21 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients of any age with clinical and radiologic diagnosis of diffuse intrinsic pontine glioma
  2. * Patients with other high-grade gliomas originating in the brainstem
  3. * Patients with focal gliomas (WHO grade I/II) of the brainstem
  1. * Patients with any type of infiltrative low grade (WHO grade I and II) or high grade glioma (WHO grade III and IV) originating outside the brainstem
  2. * Patients harboring primary brainstem tumors with other histologic diagnoses (e.g., PNET)

Contacts and Locations

Study Contact

Javad Nazarian, PhD
CONTACT
202-476-6022
JNazarian@cnmc.org
Caroline Kopsidas, BS
CONTACT
240-393-3359
ckopsidas@childrensnational.org

Principal Investigator

Javad Nazarian, PhD
PRINCIPAL_INVESTIGATOR
Children's National Research Institute

Study Locations (Sites)

Children's National Medical Center
Washington, District of Columbia, 20010
United States

Collaborators and Investigators

Sponsor: Children's National Research Institute

  • Javad Nazarian, PhD, PRINCIPAL_INVESTIGATOR, Children's National Research Institute

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2010-04
Study Completion Date2030-04

Study Record Updates

Study Start Date2010-04
Study Completion Date2030-04

Terms related to this study

Keywords Provided by Researchers

  • diffuse intrinsic pontine glioma
  • DIPG
  • childhood brainstem glioma
  • pediatric brainstem glioma
  • brainstem glioma
  • BSG

Additional Relevant MeSH Terms

  • Diffuse Intrinsic Pontine Glioma
  • Brainstem Glioma