Quality Improvement Project - Evaluation of Current Standard of Care for Feeding Practices in the NICU

Description

Human milk is associated with substantial benefits to infants' health and development, especially in premature infants. Some mothers are unable or unwilling to provide breast milk to their infant. The use of donor human milk as an alternative to cow milk in these infants has risen dramatically in the past year. However, there have been recent reports of hyperphosphatemia and hyponatremia associated with the consumption of donor human milk products. These electrolyte imbalances can lead to concerning symptoms, including headache, nausea, vomiting, altered mental status, coma, seizures, or heart failure. It is important to recognize and appropriately treat these electrolyte disturbances associated with donor human milk to avoid potential nutritional problems.

Conditions

Infant, Very Low Birth Weight

Study Overview

Study Details

Study overview

Human milk is associated with substantial benefits to infants' health and development, especially in premature infants. Some mothers are unable or unwilling to provide breast milk to their infant. The use of donor human milk as an alternative to cow milk in these infants has risen dramatically in the past year. However, there have been recent reports of hyperphosphatemia and hyponatremia associated with the consumption of donor human milk products. These electrolyte imbalances can lead to concerning symptoms, including headache, nausea, vomiting, altered mental status, coma, seizures, or heart failure. It is important to recognize and appropriately treat these electrolyte disturbances associated with donor human milk to avoid potential nutritional problems.

Quality Improvement Project - Evaluation of Current Standard of Care for Feeding Practices With Donor Human Milk Products in the NICU

Quality Improvement Project - Evaluation of Current Standard of Care for Feeding Practices in the NICU

Condition
Infant, Very Low Birth Weight
Intervention / Treatment

-

Contacts and Locations

Houston

Baylor College of Medicine / Texas Children's Hospital, Houston, Texas, United States, 77030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Premature infants (\<37 weeks gestation) with a birth weight less than or equal to 1250 grams.
  • * Infants with a birth weight greater than 1250 grams
  • * Infants transferred from an outside hospital to TCH at greater than 21 days of age
  • * Infants who do not achieve any enteral feeds by 4 weeks of age
  • * Infants with major congenital anomalies

Ages Eligible for Study

1 Day to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Baylor College of Medicine,

Amy Hair, MD, PRINCIPAL_INVESTIGATOR, Baylor College of Medicine

Study Record Dates

2025-12