Development of 3T Magnetic Resonance Research Methods for NIA Studies

Description

Background: - Magnetic resonance imaging (MRI) studies provide important information on the structure and function of various body systems, including the brain, muscles, joints, heart, and blood vessels. Scientific applications of MRI scans often use techniques that need to be modified or refined before they are used in clinical studies. To develop and modify these techniques for the new Philips 3T Achieva whole-body MRI scanner, researchers are interested in conducting trial MRI scans on healthy individuals and individuals with conditions that require imaging studies. Objectives: - To conduct preliminary trials of the 3T MRI facility to develop and refine MRI scanning procedures. Eligibility: - Individuals at least 18 years of age who are able to have magnetic resonance imaging. Design: * Participants will be screened with a full medical history and physical examination, as well as blood and urine tests. * Participants will have an MRI scan using the 3T scanner. Some scans may require the use of a contrast agent or radiotracer, which is a small amount of radioactive substance that will be injected before the start of the scan. Some participants may be asked to perform tasks of thinking and movement while in the scanner, in order to test the procedures required for a functional MRI scan. * No treatment will be provided as part of this protocol.

Conditions

Normal Physiology

Study Overview

Study Details

Study overview

Background: - Magnetic resonance imaging (MRI) studies provide important information on the structure and function of various body systems, including the brain, muscles, joints, heart, and blood vessels. Scientific applications of MRI scans often use techniques that need to be modified or refined before they are used in clinical studies. To develop and modify these techniques for the new Philips 3T Achieva whole-body MRI scanner, researchers are interested in conducting trial MRI scans on healthy individuals and individuals with conditions that require imaging studies. Objectives: - To conduct preliminary trials of the 3T MRI facility to develop and refine MRI scanning procedures. Eligibility: - Individuals at least 18 years of age who are able to have magnetic resonance imaging. Design: * Participants will be screened with a full medical history and physical examination, as well as blood and urine tests. * Participants will have an MRI scan using the 3T scanner. Some scans may require the use of a contrast agent or radiotracer, which is a small amount of radioactive substance that will be injected before the start of the scan. Some participants may be asked to perform tasks of thinking and movement while in the scanner, in order to test the procedures required for a functional MRI scan. * No treatment will be provided as part of this protocol.

Development of Magnetic Resonance Imaging and Spectroscopy Research Methods for NIA Studies

Development of 3T Magnetic Resonance Research Methods for NIA Studies

Condition
Normal Physiology
Intervention / Treatment

-

Contacts and Locations

Baltimore

National Institute of Aging, Clinical Research Unit, Baltimore, Maryland, United States, 21224

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Ability of subject to understand the study and stated willingness to comply with all study procedures.
  • * Male or female, age \> 18years.
  • * Able to speak and read English.
  • * Capable of providing informed consent.
  • * Subjects or persons identified by an investigator to have a condition of interest for exploratory studies as it relates to aging. These participants are not being scanned for diagnostic purposes.
  • * Has condition and/or non-removable device contraindicated for MRI as per the MRI eligibility form.
  • * Weight \> 300lbs (MRI scanner weight limit)
  • * Is currently pregnant or a nursing mother.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

National Institute on Aging (NIA),

Mustapha Bouhrara, Ph.D., PRINCIPAL_INVESTIGATOR, National Institute on Aging (NIA)

Study Record Dates

N/A