The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders

Description

This study seeks to determine the biologic causes of inflammation in patients with Transverse Myelitis (TM) Neuromyelitis Optica Spectrum Disorder (NMOSD) and related conditions. While patients will be treated according to decisions with their treating physician, this study will collect data and samples from patients prospectively to gain a better understanding of the disease. We are seeking to understand why some patients respond to medications, while others do not. We also seek to understand what happens biologically, preceding relapses. Gathering these data and samples will allow researchers to identify new ways of diagnosing and treating these diseases. Data and samples will be shared with researchers around the world to support collaborative efforts to treat these conditions.

Conditions

Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorder, Transverse Myelitis, Optic Neuritis

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Study Overview

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Study Details

Study overview

This study seeks to determine the biologic causes of inflammation in patients with Transverse Myelitis (TM) Neuromyelitis Optica Spectrum Disorder (NMOSD) and related conditions. While patients will be treated according to decisions with their treating physician, this study will collect data and samples from patients prospectively to gain a better understanding of the disease. We are seeking to understand why some patients respond to medications, while others do not. We also seek to understand what happens biologically, preceding relapses. Gathering these data and samples will allow researchers to identify new ways of diagnosing and treating these diseases. Data and samples will be shared with researchers around the world to support collaborative efforts to treat these conditions.

Collaboration on Neuroimmunology: Question, Understand, Educate, Restore - the Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders

The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders

Condition
Neuromyelitis Optica
Intervention / Treatment

-

Contacts and Locations

Dallas

The University of Texas Southwestern Medical Center, Dallas, Texas, United States, 75390

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 6 years or greater
  • * Male or Female
  • * Patient or Parent (in the case of a minor) able to give informed consent
  • * For patients 10 to 17, patient able to assent
  • * Patient diagnosed with NMO, NMOSD, TM or ON
  • * Unable to maintain scheduled visits
  • * Patient has known HIV or hepatitis C infection

Ages Eligible for Study

6 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Texas Southwestern Medical Center,

Benjamin M Greenberg, MD, PRINCIPAL_INVESTIGATOR, University of Texas Southwestern Medical Center

Study Record Dates

2025-06