Magnetic Resonance & Optical Spectroscopy Validation

Description

The purpose of this study is to develop and refine techniques for using magnetic resonance and optical spectroscopy to investigate how your body uses energy.

Conditions

Validation Studies, Magnetic Resonance Spectroscopy

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Study Overview

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Study Details

Study overview

The purpose of this study is to develop and refine techniques for using magnetic resonance and optical spectroscopy to investigate how your body uses energy.

Development and Validation of 31P Magnetic Resonance and Optical Spectroscopy for the Characterization of ATP in Whole Body Human Applications

Magnetic Resonance & Optical Spectroscopy Validation

Condition
Validation Studies
Intervention / Treatment

-

Contacts and Locations

Orlando

Translational Research Institute for Metabolism and Diabetes, Orlando, Florida, United States, 32804

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Male or female
  • * Age 18 - 89
  • * Healthy (self assessed)
  • * Weight under 350lbs
  • * Able to walk 50 yards without stopping
  • * Able to travel to hospital for study visits
  • * Able to follow a 3-step command
  • * Able to remain in magnetic resonance (MR) scanner for up to 2 hours
  • * Have internal metal medical devices, including cardiac pacemakers, aortic or cerebral aneurysm clips, artificial heart valves, ferromagnetic implants, shrapnel, wire sutures, joint replacements, bone or joint pins/rods/screws, metal fragments in your eye, or non-removable jewelry such as rings.
  • * Are unwilling or unable to complete the imaging procedures for the duration of the magnetic resonance imaging (MRI) scan due to claustrophobia or other reason.
  • * Serious mental illness that might preclude subject's ability to comply with study treatment
  • * Are pregnant or plan on becoming pregnant in the next 8 weeks.
  • * History of deep vein thrombosis (DVT) or pulmonary embolism (PE)
  • * Varicose Veins
  • * Known genetic factor (Factor V Leiden, etc.) or hypercoagulable state, including cancer, leukemia - such as chronic myelocytic leukemia (CML), hemoglobinopathies - such as sickle-cell disease and multiple myeloma and other proteinopathies.
  • * Diagnosed peripheral arterial or vascular disease
  • * Family history of primary DVT or PE
  • * Peripheral neuropathy
  • * History of chronic venous stasis or lower extremity edema
  • * Female taking hormonal birth control (oral or otherwise) AND smoker

Ages Eligible for Study

18 Years to 89 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

AdventHealth Translational Research Institute,

Steven R. Smith, MD, PRINCIPAL_INVESTIGATOR, Translational Research Institute for Metabolism and Diabetes

Heather Cornnell, PhD, PRINCIPAL_INVESTIGATOR, Translational Research Institute for Metabolism and Diabetes

Study Record Dates

2024-12